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(cell and molecular biology)
The initial stage of mitotic or meiotic cell division in which chromosomes are condensed from the nuclear material and split logitudinally to form pairs.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



one of the stages of mitotic cell division. During prophase of mitosis, the mitotic apparatus is formed and the chromosomes, which already consist of two sister chromatids, spiralize. In most cells, the nuclear membrane fragmentizes and the nucleolus is destroyed during prophase.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one.
The regulation of maturation promoting factor during prophase I arrest and meiotic entry in mammal ian oocytes.
A: normal interphase, A1: binuclei at interphase, A2: micronucleus at interphase, B: normal prophase, B1: binuclei at prophase, B2: micronucleus at prophase, C: normal metaphase, C1: sticky metaphase, C2: C-mitosis, D: normal anaphase, D1: anaphase bridge, and D2: multipolar.
(2014) found 38 chromosomes in mitotic metaphases and 19 bivalents during prophase I of meiosis.
By analyzing of the distribution of the pattern of constitutive heterochromatin in spermatocytes in prophase I has been possible to differentiate all species of Maculata subcomplex: T.
11 May 2017 - US-based clinical services organisation provider WIRB-Copernicus Group (WCG) has acquired data services company MedAvante and clinical trials measurement specialist ProPhase, the firm said.
The transaction is expected to close in the first quarter of 2017, pending ProPhase Labs shareholder approval and other customary closing conditions.
The wrinkling revolution process is divided into five stages: (I) prophase stage, (II) prometaphase stage, (III) metaphase stage, (IV) anaphase stage, and (V) telophase stage.
In control cultures, the percentages listed in Table S3 (http:// of the four stages of the meiotic prophase (leptotene, zygotene, pachytene and diplotene) are of the same order of magnitude as those obtained previously (Ali et al., 2014; Geoffroy-Siraudin et al., 2010, 2012).
Microspore tetrads were formed via prophase II, metaphase II, anaphase II, and telophase II (Fig.
"Folate over-supplementation and deficiency causes prophase DNA damage." (25) So obviously humans need folate, but over-supplementation with folic acid can be a problem.