Pyruvic Acid(redirected from Pyruvate metabolism)
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pyruvic acid[pī′rü·vik ′as·əd]
(α-ketopropionic acid), CH3COCOOH, a colorless liquid with a pungent odor. Melting point, 13.6°C; boiling point, 165°C. Pyruvic acid is miscible with water, ethanol, and ether in all proportions. Chemically, it behaves like ketones and carboxylic acids.
Pyruvic acid occurs in the cells of all organisms as a fundamental intermediate link in the metabolism of carbohydrates, proteins, and lipides. It accumulates in the organism as a result of various metabolic disorders, for example, vitamin-B1 deficiency. Pyruvic acid is a component in the manufacture of the pharmaceutical cinchophen. The term “pyruvate,” which in strict usage refers to the pyruvic-acid anion, CH3COCOO–, is frequently used as a synonym for “pyruvic acid” in biochemical literature.