Pyruvic Acid


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pyruvic acid

[pī′rü·vik ′as·əd]
(biochemistry)
Important intermediate in protein and carbohydrate metabolism; liquid with acetic-acid aroma; melts at 11.8°C; miscible with alcohol, ether, and water; used in biochemical research.

Pyruvic Acid

 

(α-ketopropionic acid), CH3COCOOH, a colorless liquid with a pungent odor. Melting point, 13.6°C; boiling point, 165°C. Pyruvic acid is miscible with water, ethanol, and ether in all proportions. Chemically, it behaves like ketones and carboxylic acids.

Pyruvic acid occurs in the cells of all organisms as a fundamental intermediate link in the metabolism of carbohydrates, proteins, and lipides. It accumulates in the organism as a result of various metabolic disorders, for example, vitamin-B1 deficiency. Pyruvic acid is a component in the manufacture of the pharmaceutical cinchophen. The term “pyruvate,” which in strict usage refers to the pyruvic-acid anion, CH3COCOO, is frequently used as a synonym for “pyruvic acid” in biochemical literature.

References in periodicals archive ?
The G x E interaction analysis for pyruvic acid reported a determination coefficient of 0.8% and a variation coefficient of 19.5%.
This study analyzed the in-vitro responses of the A549 and MRC-5 cell lines upon their exposure to pyruvic acid, Sodium Citrate, Sodium Bicarbonate, FDP, Zn acetate, and Oxalic acid.
Phenylpyruvic acid (PPY) (Sigma USA) pyruvic acid (PYR) 2-oxobutyric acid (KB) 3- methyl-2-oxobutyric acid (MKBA) 2-oxoglutaric acid (KG) 3-methyl 2-oxovaleric acid (K3MVA)4-methyl-2-oxovaleric acid (K4MVA) monosodium salt (Fluka Switzerland) were used.
Antisera against SGL-II and SGL-I, which are specific to 3-O-MeGal and 4-O-MeGlcNAc, respectively, stained neuropil of ganglia Furthermore, anti SGL-II antiserum stained perineural tissues Antiserum against FGL-IIb, which is specific to pyruvic acid bound to galactose at the non-reducing end of glycolipids, only stained nerve bundles distinctly.
While malic acid determines the more agreeably perceived fruity acidity, pyruvic acid is responsible for the caramel sour taste of the coffee beverage.
Propylene glycol metabolizes in the blood-stream to lactic acid and pyruvic acid, chemicals produced in the body during normal glycolysis, whereas ethylene glycol is metabolized to oxalic acid.
during glycolysis, a -- molecule is broken down into two molecules of pyruvic acid. 4.
The glucose so produced or the glucose absorbed from diet undergoes a series of reactions through anaerobic glycolytic pathway in the tissues to produce pyruvic acid and then lactic acid or the pyruvic acid undergoes oxidative decarboxylation to form acetyl Co-A which is channelised into aerobic Kreb's cycle, which in its cycle generates reduced nucleotides (NADH and FAD) for the ultimate generation of biological currency, ATP through electron transport system.
A modified spectrophotometric method for the analysis of pyruvic acid, a compound of agricultural and medical significant is described.
The pungency of onions can be rated on a numeric scale based on the amount of pyruvic acid present in the bulbs.
Additionally, Hb adducts with pyruvic acid at the amino terminus of the [beta]-chain (in [HbA.sub.1b]) (15) or glycoinositolphospholipid at the carboxy terminus of the [beta]-chain (16) are known.