Pyruvic Acid

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pyruvic acid

[pī′rü·vik ′as·əd]
Important intermediate in protein and carbohydrate metabolism; liquid with acetic-acid aroma; melts at 11.8°C; miscible with alcohol, ether, and water; used in biochemical research.

Pyruvic Acid


(α-ketopropionic acid), CH3COCOOH, a colorless liquid with a pungent odor. Melting point, 13.6°C; boiling point, 165°C. Pyruvic acid is miscible with water, ethanol, and ether in all proportions. Chemically, it behaves like ketones and carboxylic acids.

Pyruvic acid occurs in the cells of all organisms as a fundamental intermediate link in the metabolism of carbohydrates, proteins, and lipides. It accumulates in the organism as a result of various metabolic disorders, for example, vitamin-B1 deficiency. Pyruvic acid is a component in the manufacture of the pharmaceutical cinchophen. The term “pyruvate,” which in strict usage refers to the pyruvic-acid anion, CH3COCOO, is frequently used as a synonym for “pyruvic acid” in biochemical literature.

References in periodicals archive ?
This study analyzed the in-vitro responses of the A549 and MRC-5 cell lines upon their exposure to pyruvic acid, Sodium Citrate, Sodium Bicarbonate, FDP, Zn acetate, and Oxalic acid.
While the content of formic acid, acetic acid and quinic acid partially increased marginally, the concentration of pyruvic acid is altogether lower than during the initial measurement.
Pyruvic acid is an organic keto acid that has an essential role in biological energy production [1].
1b] fraction isolated from a patient with glycogenose type I includes peaks that correspond to the [alpha]-chain (15 127 Da), the pyruvic acid adduct of the [beta]-chain (15 938 Da), and the latter's decarboxylated form (15 894 Da).
Rather than being genetically modified, the onion has been specially bred and grown in low-sulphur soils, which halves its pyruvic acid content--the substance that irritates tear ducts, skin and nostrils when an onion's flesh is cut and exposed to the air.
Rather than being genetically modified, the new onion has been specially bred and grown in low-sulphur soils to cut its pyruvic acid content by half.
Onions cause tears because they contain high quantities of pyruvic acid which is released when an onion is cut and exposed to the air.
Thiamin-deficient pigs have elevated blood pyruvic acid and lactic acid levels and reduced appetite.
Pyruvic acid causes tears to stream down chefs' cheeks, in an effort to repel the fumes.
It's the pyruvic acid in sulfur that causes one's eyes to sting and tear when cutting onions, and it can sometimes cause indigestion.
According to the company, its Creapure Citrate is the ideal solution regarding taste and solubility and its Creapure Purovate (protected by compostion, manufacturing and application patents) is an ideal combination of creatine and pyruvic acid in a 60:40 ratio, which brings together the power of creatine and the endurance of pyruvate.
25 SCIENCE that such conditions create pyruvic acid, an organic chemical vital to cellular metabolism.