Additionally, other compounds were also important for both assays (quinic acid
, 3-p-coumaroylquinic acid, 5-0-caffeoylquinic acid, and kaempferol hexoside).
derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia.
glutinosa) contained seven polysaccharides (1- 7), chlorogenic acid (8), 3,4-dicaffeoyl quinic acid
(11), 3,5-dicaffeoyl quinic acid
(12), and 4,5- dicaffeoyl quinic acid
A typical break-down product of chlorogenic acid is the quinic acid
as mentioned above.
AC-11 and AIO samples were measured against standards of Dioctyl Phthalate (DOP) and Quinic Acid
Lactone (QAL) with maximum absorbance at 505 and 520 nm, respectively.
Furthermore, Haslam (1993) has suggested that quinic acid
may be formed as a result of overflow metabolism of the shikimate pathway.
Chlorogenic acids are phenolic acids that result from the esterification of quinic acid
(QA) and cinnamic acid (CA) derivatives including caffeic, sinapic, and ferulic acid .
Apart from them, other polar compounds were also found; they are quinic acid
, caffeoylquinic acid isomers, and benzyl alcohol hexose-pentose.
In this group, the most abundant metabolite was quinic acid
, which significantly increased its production (2.18-fold, p = 0.0053).
latifolia roots contain terpenes; taraxasteryl myristate, taraxasteryl acetate, motiol, 3-[beta]-hydroxy fern-8 en-7-one acetate, urs-12-en-11-one-3-acetyl, 3-[beta]-hydroxy-fern-7-en-6-one-acetate, olean-12-en-11-one-3-acetyl, fern-7-en-3-[beta]-one, leucodin, [beta]-sitosterol (22-24), phenolic compounds; chlorogenic acid, chlorogenic acid methyl ester, 1,5-dicaffeoyl quinic acid
, 3,5-dicaffeoyl quinic acid
, methylester of 3,5-dicaffeoyl quinic acid
, hydrangenol-8-O-glucoside, hydrangenol-4'-O-glucoside, scorzotomentosin-4'-O-glucoside and a new isocoumarine derivative (25) as well as scorzoveratrin 4'-O-[beta]-glucoside, scorzoveratrin, scorzoveratrozit, 4,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid methyl ester and caffeic acid.
is tungtungmadic acid which is chlorogenic derivative; while chlorogenic acid is the ester of caffeic acid with quinic acid
which mainly exhibits antioxidative functions (Chung et al., 2005; Bonita et al., 2007).
Compound 3, with a similar structure, showed lower inhibition of AR because it has a methyl group instead of quinic acid
. Flavonoid compounds also showed high inhibition of RLAR.