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However, the mechanism of RIHD remains largely unknown and there is currently an urgent need to elucidate the mechanism of RIHD, in order to develop effective therapies for this condition.
Cardiac catheterizations for congenital heart disease, radiation therapies for cancer, and radiation exposures from all medical sources, during which the heart is unavoidably irradiated, can cause irreversible cardiac injury and even cardiac failure.[sup][13] The severity of RIHD has been reported.
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