RIP

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Related to RIPK1: necroptosis, PubMed

rip

Informal, archaic
an old worn-out horse

rip

[rip]
(engineering)
To saw wood with the grain.
(mining engineering)
To break down the roof in mine roadways to increase the headroom for haulage, traffic, and ventilation.
(oceanography)
A turbulent agitation of water generally caused by the interaction of currents and wind.

RIP

[¦är¦ī¦pē or rip]
(graphic arts)

rip

To cut wood lengthwise, parallel to the grain.

RIP

(networking)

RIP

(application, printer)

rip

(audio)
(From "rip off" - to steal) To copy audio or video (e.g. from a compact disc) to a file, e.g. an MP3 digital audio file, on a computer hard disk.

While it may be legal to do this for personal use, ripping a copyright work and distributing the result to others could result in prosecution.

RIP

(1) (rip) To convert optical media into a totally electronic format. See ripping.

(2) (Raster Image Processor) The hardware and/or software that prepares data for display or printing. See rasterize. See also image processor.

(3) (Routing Information Protocol) A simple routing protocol that is part of the TCP/IP protocol suite. It determines a route based on the smallest hop count between source and destination. RIP is a distance vector protocol that routinely broadcasts routing information to its neighboring routers and is known to waste bandwidth. It also has a limit of 15 hops. If a route is advertised as having 16 hops, it is flagged as unreachable. All earlier networks (AppleTalk, NetWare, VINES, DECnet) used their own incompatible versions of RIP. See routing protocol.

(4) (Remote Imaging Protocol) An earlier graphics format from TeleGrafix Communications, designed for transmitting graphics over low-speed lines. Using a communications program that supported RIP enabled graphical interfaces to be used on a BBS with respectable performance via modem.
References in periodicals archive ?
Another essential finding from this study is the meaningful confirmation of RIPK3 but not RIPK1 as being significantly upregulated in human livers.
Zelic et al., "RIPK1 and RIPK3 kinases promote cell-death-independent inflammation by toll-like receptor 4," Immunity, vol.
Caption: Figure 2: RIPK3, but not RIPK1, is highly expressed in patients with alcoholic cirrhosis.
Membranes were subsequently blocked with 5% skim milk in Tris-buffered saline and Tween 20 (TBST) solution for 2h and were incubated with primary antibodies at 4[degrees]C overnight: RIPK3 (Cell Signaling, number 14401), RIPK1 (Cell Signaling, number 3493), GRP78 (Cell Signaling, number 3183), Phospho-mTOR (Ser2481) (Cell Signaling, number 2974), mTOR (Cell Signaling, number 2983), Calreticulin (Cell Signaling, number 12238), AKT (Cell Signaling, number 4685), and Phospho-AKT (Ser473) (Cell Signaling, number 4058).
Images were collected using an Eclipse TE2000-U fluorescence microscope system (Nikon, Japan) and analyzed with ImageJ software (NIH, USA) to semiquantitatively determine the expression of RIPK1 and RIPK3.
For this purpose, we first detected the gene expression of RIPK1 and RIPK3.
The expression of RIPK1/RIPK3 protein obtained by immunofluorescence staining also indicated that growth-arrested H9c2 cells presented a slight RIPK1 and RIPK3 staining, while treatment with PA for 24 h significantly increased cytoplasmic RIPK1/RIPK3 staining (Figures 2(c) and 2(d)).
Our findings also show that regulated death at an acidic pH relies not only on the function of RIPK1, caspase-8, but also PARP-1, implicating parthanatos [41] as well as apoptosis and necroptosis.
The RIPK1 inhibitor Nec-1s, which blocks necroptosis, was added to cultures at pH 7.4 (Figures 2(a) and 2(d)), pH 6.7 or pH 6.0 (Figures 2(b), 2(c), and 2(d)).
Death in endothelial cells at an acidic pH relies on the function of RIPK1 and caspase-8 (Figures 2 and 3).
RIPK1, RIPK3, caspase-8, and PARP-1 all appear to be necessary to induce necrotic death with TRAIL at low pH.