RNA primer


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Related to RNA primer: Okazaki fragments

RNA primer

[¦är¦en¦ā ′prī·mər]
(cell and molecular biology)
A short strand of RNA that is synthesized along single-stranded DNA during replication, initiating DNA polymerase-catalyzed synthesis of the complementary strand.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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coli RNA primers. A year later, Beljanski was able to show that these short-chain RNA fragments could serve as promoters of leucocytes and platelets in animals depleted by anticancer drugs.
One would think that all patients receiving conventional chemotherapy and radiation might benefit from treatment with these RNA primers. However, since they are not patentable drugs (as they are natural products) and the amount of money required to go through the procedures of the Food and Drug Administration (FDA) for them to become approved as a drug is astronomical for a small supplement company, it is difficult to see how they can be brought to the attention of the health-care community.
To replicate the lagging strand, DNA polymerization starts from several RNA primers, which are elongated to create DNA fragments termed Okazaki fragments.