This US FDA breakthrough therapy designation was based on clinical data from the company's prophylactic RSV
senior vaccine that may demonstrate substantial improvement compared to available standard of care on a clinically significant endpoint(s).2
'With no preventive vaccines or effective antiviral treatments currently available, RSV
remains a significant cause of illness in at-risk populations, particularly older adults,' said Johan Van Hoof, M.D., Global Therapeutic Area Head, Vaccines, and Managing Director, Janssen Vaccines & Prevention B.V., Janssen Pharmaceutica N.V.
Hoffman-La Roche Ltd., Danaher Corporation, Quest Diagnostics, Biocartis, Luminex, Hologic, Fast Track Diagnostics, Biomerieux, Becton, Dickinson, and Company (BD), Alere, Inc., Quidel Corporation, Thermo Fisher Scientific are among some of the top most companies in the RSV
It is unclear what proportion underwent RSV
testing, but a total of 334 were confirmed RSV
positive: 261 were SI, 54 were CMD, and 19 were NMD.
Since July 2007, we have been monitoring for RSV
infection among hospitalized children with pneumonia in Beijing, China.
This shift toward an overall increasing percentage of cases with reported PCR detections since 2013 corresponds with the noted shift in age distribution among reported RSV
A review of RSV
infections in the Middle East region (11) shows that, similar to other parts of the world, RSV
infections occurring the winter and peak around January, with the same age groups affected.
A strong interleukin-8 (IL-8)-mediated neutrophil response is the first response against RSV
infection in the body, which is related with the disease severity.
Therefore, the present study was undertaken to determine the efficacy of cell culture, immunofluoescent assay (IFA) and real time Polymerase hain eaction (rRT-PCR) in relation to diagnosis of influenza and RSV
Conclusion: Data confirms a year-round presence of RSV
in Puerto Rico.
Researchers concluded that data suggest high-dose RSV
supplementation positively affects bone, primarily by stimulating formation or mineralization.