Effects of the antiprogesterone RU 486
in early pregnancy and during the menstrual cycle.
This commentary explains the legal and regulatory status of RU 486
as used in combination with prostaglandin in France and addresses some of the legal questions that countries, including the United States, will have to face as they consider approval of this and other antiprogestin drugs for abortifacient purposes.
Feminist groups, particularly the Feminist Majority Foundation, lobbied Roussel to bring RU 486
to the United States, but to no avail.
Croxatto, "Effects of RU 486
on Development and Implantation of Rat Embryos," Molecular Reproduction and Development, 29:342-346, 1991.
b) RU 486
In Combination With Misoprostol Presents Separate Risks And Safety Concerns
The difference was that Kessler had stated the company's intent to turn over US rights to RU 486
to the Population Council, but a formal contract had yet to be signed.
The realities associated with the use of RU 486
belie any such suggestion.
A bill is pending in the Minnesota legislature that would appropriate money for use of RU 486
in family planning and for the treatment of disease.
Roussel had been reluctant to bring RU 486
to the United States because of opposition by the antiabortion movement.
She tells me they're doing a study on a nonsurgical procedure similar to RU 486
Some may argue, incorrectly, that pregnancy begins at fertilization, and if RU 486
acts by preventing implantation of the fertilized ovum, the result is an abortion.
is also used in cases of difficult and prolonged labor, often reducing the need for a caesarean section.