Here, syphilis serology was performed using treponemal haemagglutination (TPHA) and rapid plasma reagin
(RPR) tests (Abbott biokit).
The patient's test results were negative for gonorrhea, Chlamydia, and human immunodeficiency virus, with a nonreactive rapid plasma reagin
test result in 2008.
Laboratory testing was performed: the erythrocyte sedimentation rate was 49 mm/h (reference 0-22 mm/h), and test results were negative for human leukocyte antigen B27, angiotensinconverting enzyme, rapid plasma reagin
, and antinuclear antibody.
CDC recommends syphilis serologic screening with a nontreponemal test, such as the rapid plasma reagin
(RPR) or Venereal Disease Research Laboratory (VDRL) test, to identify persons with possible untreated infection; this screening is followed by confirmation using one of several treponemal tests.
Commonly used nontreponemal tests include the rapid plasma reagin
(RPR) test and the Venereal Disease Research Laboratory (VDRL) test.
One week later, the rash had not resolved and the patient demanded a syphilis test; a 1:8 ratio on the rapid plasma reagin
(RPR) test indicated syphilis; a confirmatory fluorescent treponemal antibody-absorption double staining (FTA-ABS) test also was reactive.
If all the usual serologic tests (toxoplasma, Bar-tonella, rapid plasma reagin
, tularemia, hepatitis) come up negative, and the apparent mono and adenopathy persist, cancers rise in the differential diagnosis.
A rapid plasma reagin
(RPR) assay (RPR Reditest; Biokit) was used to determine whether seropositivity was caused by recent infection.
A complete blood count, basic metabolic panel, and urinalysis were all within normal limits; a rapid plasma reagin
(RPR) was nonreactive.