rate-determining step

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rate-determining step

[′rāt di¦tər·mən·iŋ ‚step]
(chemistry)
In a multistep chemical reaction, the step with the lowest velocity, which determines the rate of the overall reaction.
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Without arbitrary assignments regarding the rate determining step of propagation, isothermal grafting kinetics can be described adequately using an expression that captures the behavior of VTEOS additions as well as those of related modification reactions.
Due to the presence of k1 in the rate low (IX), it is obvious that first step ([k.sub.1]) is a rate determining step. In this case, the transition state (see step 1, Figure 11) in reaction carries a dispersed charge, effect of solvent (mixture of water and ethanol, 50%: 50%), which has higher dielectric constant ([epsilon] = 52.12) rather than a mixture of water and methanol (20: 80) (with lower dielectric constant [epsilon] = 42.08) on this dispersed charge which would be much stronger compared to that on reactants (2 and 1) that do not have any charge.
The small salt effect suggests the participation of neutral species in rate determining step i.e., the substrate molecule and HOCl.
The positively charged complex then reacts further with the protonated vanadium in the slow and rate determining step.