rate-determining step

(redirected from Rate limiting step)
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rate-determining step

[′rāt di¦tər·mən·iŋ ‚step]
(chemistry)
In a multistep chemical reaction, the step with the lowest velocity, which determines the rate of the overall reaction.
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In contrast, MB7133 is designed to bypass the rate limiting step in the liver cell and result in production of high levels of the tumor killing form of the drug.
It has become clear in the field of RNAi that delivery is the rate limiting step.
Elixir's Vice President of Medical Development and first author of the study, commented, "The known activity of MTP, as a rate limiting step in lipid metabolism, lends functional credibility to our association of MTP with human longevity.
Manufacturing of these products is proving a rate limiting step in fully commercializing many antibodies, and some experts predict that manufacturing demand will outstrip supply by two to four times over the next few years.
Previously, we viewed the rapid collection of genotypic data as a rate limiting step in our genome program.