(redirected from Reflux nephropathy)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.


Any disease of the kidney.



a general term that includes several renal disorders. Classified as nephropathies are nephropathy of pregnancy and a group of other kidney diseases that are distinguished from each other by a variety of morphological changes. This latter group of diseases includes myelogenous nephropathy, endemic, or Balkan, nephropathy, medicinally induced nephropathy, kaliopenic nephropathy, and hypercalcemic nephropathy.


Osnovy nefrologii, vol. 2. Edited by E. M. Tareev. Moscow, 1972.
References in periodicals archive ?
Diabetic nephropathy (a) 28 Hypertensive nephropathy 11 Focal segmental glomerulosclerosis (b) 7 Collapsing glomerulopathy (c) 2 Granulomatous tubulointerstitial nephritis (d) 2 Acute pyelonephritis 1 Thrombotic microangiopathy 1 Atheroembolic disease 1 Reflux nephropathy (e) 1 Proliferative glomerulonephritis (f) 1 Membranous glomerulonephritis (g) 1 Amyloidosis 1 (a) All patients had clinical diabetes.
The operative hypothesis up until the current guidelines were released in 2011 (Pediatrics 2011;128:595-610) was that identifying reflux via a voiding cystourethrogram (VCUG) allowed physicians to intervene surgically or with prophylactic antimicrobials to prevent further reflux nephropathy with further scarring.
We do know the incidence of end-stage renal disease and hypertension from reflux nephropathy is much lower than was previously thought, but now some adult medicine journals are suggesting that 40- and 50-year-olds with renal scarring have a higher incidence of hypertension.
In children with VUR, renal scarring and subsequent risk of reflux nephropathy are associated with UTIs, high VUR grade and abnormal lower urinary tract function.
It is based on a paradigm for reflux nephropathy now in disrepute.