interpretability

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interpretability

The suitability of imagery for interpretation with respect to answering adequately requirements on a given type of target in terms of quality and scale.
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The Willowbrook hepatitis experiments, where healthy children were deliberately infected in a context in which the disease was endemic, and the Kennedy Kreiger lead abatement study, where low-income families with young children were given incentives to live in houses with the hazard of lead paint to test biological effects of new removal methods, are frequently offered as examples of the danger of a relative interpretation. (73) Hence it seems that the relative interpretation of minimal risk as a limit on research with the vulnerable also fails by the standard of justice.
Nonetheless, as we saw above, the Preamble to 45C.F.R.46 continues to embody a relative interpretation, and arguments are made in the ethics literature to defend this interpretation.
In this sense, both proponents and critics of the relative interpretation agree in the case of "therapeutic" research to using the term "minimal risk" as what we might call a kind of "regulatory fiction." The concept marks a limit on research with vulnerable individuals, while at the same time ensuring that vulnerable groups in the long run have access to the benefits of research--but it accomplishes this by counting research as "minimal risk" that is not, however, remotely consistent with ordinary meaning of the phrase "minimal risk," such as brain surgery or chemotherapy.
It is possible that such complacency with this shared feature of the relative interpretation of minimal risk and clinical equipoise is related to the common mistake of understanding such research risk as substitutive.
While research ethics guidelines and regulations may need to specify more rigorous limits to "minimal risk" than the phrase carries in ordinary language, the relative interpretation defines these words such that what would not be labelled "minimal risk" in ordinary language would be labelled "minimal risk" in its technical sense.
On the relative interpretation, what otherwise would pass as greater than minimal risk for the average population, i.e.

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