Relaxants


Also found in: Dictionary, Thesaurus, Medical.

Relaxants

 

substances that decrease the tonus of skeletal musculature, which is manifested by a decrease in motor activity to the point of complete immobility.

Depending on the way in which they act, relaxants are classified as curariform agents, which block transmission of excitation through the neuromuscular synapse, that is, from the motor nerves to the muscle (such relaxants are used in anesthesiology for the complete relaxation of musculature), and centrally acting substances, which influence the central nervous formations that participate in the regulation of muscle tonus. Centrally acting relaxants, such as Meprotan and Mydocalm, are used in neurological practice to treat cerebrospinal and cerebral spastic paralysis, parkinsonism, and other disorders.

References in periodicals archive ?
Effects of acute and repeated doses of two muscle relaxants chlormezanone and thiocoside, on vigilance and psychomotor performance of healthy volunteers.
The study did not look into how the use of muscle relaxants might cause the negative effects.
The researchers did not look into how the use of muscle relaxants might cause the negative effects.
Laparoscopic surgery and muscle relaxants: is deep block helpful?
Anesthetic management using remifentanil target controlled infusion without muscle relaxants in two patients with myasthenia gravis.
Therefore, myasthenic patients are sensitive to nondepolarizing muscle relaxants (Baraka, 1992), including cisatracurium (Baraka, Siddik, & Kawkabani, 1999), and requirements for them during anesthesia are patient dependent (Baraka et al., 1999; Nilsson & Meretoja, 1990).
Muscle relaxants. New substances and neuromuscular monitoring.
Product coverage: 2-in-1 Products, Colourants, Conditioners, Hair Loss Treatments, Perms and Relaxants, Salon Hair Care, Shampoos, Styling Agents.
Geoffrey Organe et al reported investigating various agents thought to be muscle relaxants in 1949 (6).
Our ED at the university pretty much doesn't hand out muscle relaxants anymore.
One of the most striking findings was a mortality rate six times higher in the group receiving muscle relaxants. Based on these data, the group of researchers published the following recommendations: to improve neuromuscular blocking agents, to follow good practices, and to design monitoring devices (1).