References in periodicals archive ?
Shana McCormack et al, "Pharmacologic targeting of sirtuins and PPAR signaling improves longevity and mitochondrial physiology in respiratory chain complex I mutant Caenorhabditis elegans," Mitochondrion, published online March 3, 2015 and in May 2015 print issue.
Analysis of mitochondrial ATP production rate (20) and respiratory chain enzyme complex I(23), II, I+III, II+III, IV, and CS (22, 24) activity were performed as previously described.
53,54) Respiratory chain dysfunction was subsequently identified, confirming the primary mitochondrial dysfunction as the cause of the syndrome in these cases.
Scientists of the University of Freiburg and the University of Frankfurt say that after ten years of research work, the x-ray crystallographic analysis of the huge and most complicated protein complex of the mitochondrial respiratory chain was successful.
She was posthumously diagnosed with mitochondrial respiratory chain disease.
The mitochondrial respiratory chain is a powerful source of reactive oxygen species, which are thought to play a major part in the deterioration of cell structures accompanying ageing.
3NP has long been known to inhibit succinate dehydrogenase activity of the Krebs cycle and the respiratory chain in mitochondria.
A dysfunctional mitochondrial respiratory chain can affect all organs and tissues and cause a wide variety of disorders.
Mitochondrial electron transport system: see Respiratory chain.
Key Words: metabolic myopathy, mitochondrial myopathy, side effect, adverse reaction, neuromuscular disorder, respiratory chain
The cytochrome-c-oxidase is a mitochondrial enzyme, present in the terminal segment of the respiratory chain, it plays a significant role in oxidative phosphorylation to yield ATP.
which is taken up into dopaminergic neurons, where it selectively inhibits complex I of the mitochondrial respiratory chain and leads to degeneration of these nigrostriatal neurons.