retrotransposon

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Related to Retroelements: Retrotransposition

retrotransposon

[¦re·trō·tranz′pō‚zän]
(cell and molecular biology)
A small, mobile deoxyribonucleic acid (DNA) sequence that can retrotranspose, that is, move from one genomic location to another by producing ribonucleic acid (RNA) that is transcribed by reverse transcriptase back into DNA which is then inserted at a new site.
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References in periodicals archive ?
So Goff's group examined where in the sick clams' genome the retroelement landed, sampling clams from multiple locations along the Eastern Seaboard.
I believe that such conditions, which include Aicardi-Goutieres syndrome (AGS), spondyloenchondrodysplasia, and some cases of systemic lupus erythematosus (SLE), can usefully be considered to represent a novel set of inborn errors of immunity, and that the recognition of diseases as type I interferonopathies will have significance for the development of targeted therapies, as well as informing our understanding of viral and retroelement biology, and the pathogenesis of some forms of autoimmunity.
Methylation of endogenous human retroelements in health and disease.
Retroelements use a copy-and-paste process instead of the cut-and-paste process of transposons.