Reye's syndrome

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Related to Reye Syndrome: aspirin, black mass

Reye's syndrome

(rīz), rare but life-threatening disease characterized by acute encephalopathy and fatty infiltration of internal organs, especially the liver. It occurs almost entirely in children under age 15. The cause is unknown, but the disease usually follows an acute viral infection (particularly influenza or chicken pox), especially when aspirinaspirin,
acetyl derivative of salicylic acid (see salicylate) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and
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 or other salicylates have been given. The symptoms, which occur about a week after the virus infection, are vomiting and disorientation; these may be followed by seizures, coma, and respiratory arrest. Treatment is directed toward reducing brain swelling, correcting blood chemistry changes due to liver damage, and providing respiratory support if needed. Doctors recommend that children be given acetaminophenacetaminophen
, an analgesic and fever-reducing medicine. It is an active ingredient in many over-the-counter medicines, including Tylenol and Midol. Introduced in the early 1900s, acetaminophen is a coal tar derivative that acts by interfering with the synthesis of
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 rather than aspirin for viral infections or feverfever,
elevation of body temperature above the normal level, which in humans is about 98°F; (37°C;) when measured orally. Fever is considered to be a symptom of a disorder rather than a disease in itself.
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.

Reye's syndrome

[′rīz ‚sin‚drōm]
(medicine)
An uncommon liver disorder primarily occurring in infants and young children; characterized by convulsions, hypoglycemia, and a liver showing diffuse microvacuolar fatty metamorphosis.
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References in periodicals archive ?
The infant died, and her condition was diagnosed as Reye syndrome after postmortem pathologic examination.
The clinical symptoms of the patients infected with NII561-2000-related viruses were gastroenteritis, respiratory symptoms, rash, and flaccid paralysis in addition to Reye syndrome (Table 5), and these disease categories were similar to those of other HPeVs (2,3).
In this study, we isolated a novel HPeV (NII561-2000) from a 1-year-old girl with Reye syndrome and determined the nucleotide sequence.
The NII561-2000 virus was originally isolated from a patient with Reye syndrome, an acute noninflammatory encephalopathy characterized by an antecedent viral infection, such as influenza or varicella (10-12).
This presentation will focus on the description of Reye Syndrome and the common conditions presenting like it, their treatment and the importance of recognition of those common conditions presenting like Reye Syndrome in the 21st century.
Since the association between Reye Syndrome and aspirin was established and the Reye Syndrome warning label was required, most physicians do not recommend aspirin products for children or young adults, resulting in fewer Reye Syndrome cases.
Giving children aspirin may increase the risk of Reye syndrome, a rare but serious illness associated with flu and other viral diseases, including chickenpox.