Südhof, Thomas Christian

Südhof, Thomas Christian,

1955–, German-American biochemist. M.D., b. Göttingen, Germany, Ph.D. Georgia Augusta Univ., Göttingen, 1982. Südhof joined the faculty at the Univ. of Texas Southwestern Medical Center in 1983. He became an investigator of the Howard Hughes Medical Institute in 1991 and professor at Stanford in 2008. Südhof has done extensive research on synapsessynapse
, junction between various signal-transmitter cells, either between two neurons or between a neuron and a muscle or gland. A nerve impulse reaches the synapse through the axon, or transmitting end, of a nerve cell, or neuron.
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 and transmission of signals across synapses by neurotransmitters, with particular focus on the release of neurotransmitters. He shared the 2013 Nobel Prize in Physiology or Medicine with Randy SüdhofSüdhof, Thomas Christian,
1955–, German-American biochemist. M.D., b. Göttingen, Germany, Ph.D. Georgia Augusta Univ., Göttingen, 1982. Südhof joined the faculty at the Univ. of Texas Southwestern Medical Center in 1983.
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 and James RothmanRothman, James Edward,
1950–, American cell physiologist, b. Haverhill, Mass., Ph.D. Harvard, 1976. Rothman was a professor at Stanford from 1978 to 1988 and at Princeton from 1988 to 1991.
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 for their discoveries concerning the regulation of vesicle traffic (a major transport system in body cells). Südhof uncovered the mechanism by which vesicles are signaled to release their cargo—for example, hormones and enzymes—with precision.
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