Transaminase

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transaminase

[¦tranz′am·ə‚nās]
(biochemistry)
One of a group of enzymes that catalyze the transfer of the amino group of an amino acid to a keto acid to form another amino acid. Also known as aminotransferase.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Transaminase

 

(also aminotransferase and aminopherase), an enzyme of the transferase group that catalyzes the transfer of an amino group (—NH2) from an α-amino acid to an α-keto acid. Transaminases are found in most animal and plant tissues and play an important part in nitrogen metabolism. The role of transaminase in the transamination process was discovered by the Soviet biochemists A. E. Braunshtein and M. G. Kritsman in 1937. The coenzyme in transaminase reactions is pyridoxal phosphate, the aldehyde group of which serves as intermediate acceptor of the amino group. The resulting pyridoxamine phosphate transfers the amino group to the ketone group of the acid undergoing amination. The reaction is reversible.

A. A. BOLDYREV

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Severe Poisoning CPK SGOT SGPT Mean 843.68 157.54 138.32 N 41 41 41 SD 13.0205 52.7101 49.1322 Minimum 564.50 32.00 33.00 Maximum 1100.00 301.00 288.00 Range 535.50 269.00 255.00 Association of Respiratory Failure in Organophosphorus Poisoning with CPK, SGOT, and SGPT
5: SGPT in Liver Disease and Non-Liver Disease SGPT SGPT >40 IU/L <40 IU/L Liver Disease Patients 72% 28% Non Liver Disease Patients 70.60% 29.40% Note: Table made from bar graph.
Bilirubin SGOT SGPT Renal (total in (IU/L) (IU/L) Doppler mg/dl RI Mean 2.46 55.33 52.67 0.5253 SD 0.92 8.97 7.64 0.1488 0.2073 Table--2: Group B Na K Albumin (meq/dl) (meq/dl) Mean 144.93 4.18 3.75 SD 7.44 0.62 0.32 Creatinine Urea (mg) Bilirubin SGOT SGPT Renal (mg) (total in (IU/L) (IU/L) Doppler mg/dl RI Mean 1.25 34.47 3.86 111.27 70.20 0.62 SD 0.66 10.67 5.22 147.98 99.84 0.09 Corr.
At the age of 19 weeks, serum samples were collected from 4 birds per replicate for the determination of SGPT (Alanine Aminotransferase) and SGOT (Aspartate Aminotransferase) by means of auto analyzer using commercially available kits purchased from the Accurex biomedical company.
For parameters like SGPT (L1), SGOT (L1), Creatinine (L1) and Cholesterol (L2), the sigma values were found to be less than 3.
Table 1: Liver enzymes value before and after withdrawal of clonazepam-indicating acute liver injury Liver function test Day 1 (before) Day 2 (before) Day 1 (after) SGOT 40.3 59.7 32.8 SGPT 45.6 50.2 32.0 ALP 135.3 150.9 135.0 Bilirubin 1.10 0.13 0.4 Liver function test Day 2 (after) SGOT 31.0 SGPT 31.5 ALP 131.3 Bilirubin 0.2 SGOT: Serum glutamic oxaloacetic transaminase, SGPT: Serum glutamic pyruvic transaminase, ALP: Alkaline phosphatase
In the present study, the elevated level of serum bilirubin (mean serum bilirubin 7.93 mg/dl) and the liver enzyme SGPT (mean SGPT 881.45 IU/L) were found in all the HEV-positive patients with acute infection among the pregnant women population.
In Toxocara canis infected dogs, SGOT and SGPT mean and SE values were 129.07[+ or -]1.98 IU/L and 125.81[+ or -]2.21 IU/L, while in control group these values increased up to 152.03[+ or -]1.20 IU/L and 151.34 [+ or -]1.31 IU/L, respectively.
Increasing of SGPT and SGOT level after diabetes induction which was compensated by honey signifiantly (P<0.05).
Clinical efficacy was assessed by stratification of serum ferritin, creatinine and serum glutamic pyruvic transaminase (SGPT) values and further evaluated by paired sample test.
We measured 9 biochemical parameters glucose, cholesterol, triglycerides, urea, creatinine, total bilirubin, AST (SGOT), ALT (SGPT), iron.
I would like to take this opportunity to express my warmest congratulations to the Times of Oman for its achievements and the innovation and initiatives it continues to undertake." "The executive health screening package will include laboratory investigations, complete blood count (CBC), ESR, FBS - fasting blood sugar, HBA1c, urine routine and total cholesterol in addition to LDL, HDL, Triglycerides, SGOT and SGPT. The package also includes Creatinine (Serum), Urea (blood), Uric Acid, investigations, chest x-ray and ECG.