RNA

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Related to SNRNA: spliceosome, hnRNA

RNA:

see nucleic acidnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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RNA

(biochemistry)

RNA

Biochem ribonucleic acid; any of a group of nucleic acids, present in all living cells, that play an essential role in the synthesis of proteins. On hydrolysis they yield the pentose sugar ribose, the purine bases adenine and guanine, the pyrimidine bases cytosine and uracil, and phosphoric acid
References in periodicals archive ?
The spliceosome is a massive ribonucleoprotein complex comprising some small "U"s nuclear RNAs (snRNAs) plus different specific proteins, these complexes being referred to as small nuclear ribonucleoproteins (snRNPs or SNURPs).
RNAsplicing is executed by a complex of proteins and small nuclearRNAs(snRNAs) called the spliceosome.
A group of RNAs, small nuclear ribonucleic acids (snRNAs), is required for eukaryotic cell life by virtue of the activity within a larger complex called the spliceosome.
We tested whether this "retro-evolution" approach could be a useful tool for exploring the origin and function of the small nuclear RNAs (snRNAs) of the mammalian spliceosome.
In this regard, noncoding RNAs (ncRNAs) [5] in the blood of cancer patients, comprising small nucleolar RNA (snoRNA), microRNA (miRNA), piwi-associated RNA, small Cajal body--specific RNA (scaRNA), and small nuclear RNA (snRNA), have been suggested as novel biomarkers for noninvasive cancer diagnosis.
The cycle threshold was collected from each reaction, and the relative expression level of each miRNA to U6 snRNA was evaluated using the equation 2-(CTmiRNA-CTU6snRNA), and the fold-change (log2-ratio) was used to show the differential expression pattern of miR-184 in different samples (Saleh et al.
EXOSOME PROTEINS MAY BE INVOLVED IN SNRNA BIOGENESIS.
The relative quantification was calculated by comparative threshold (Ct) cycle method ([2.sup.-[DELTA][DELTA]Ct]) and normalized with U6 SnRNA or GAPDH mRNA.
The ratio of each miRNA relative to the endogenous U6 snRNA was calculated using the 2-aact method.
A cohort of five reference genes was simultaneously analysed for the normalization process (18S rRNA, RNU43, GAPDH, LAMIN A/C, and U6 snRNA), and the optimum reference genes were identified using NormFinder algorithm [27].