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jab

1. a quick short blow, esp (in boxing) a straight punch with the leading hand
2. Informal an injection
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References in periodicals archive ?
Chen et al., "Downregulated SOCS1 expression activates the JAK1/STAT1 pathway and promotes polarization of macrophages into M1 type," Molecular Medicine Reports, vol.
Decreased glucose levels have been detected in SOCS1 knockout mice, and cells derived from these mice exhibited increased insulin signaling (8).
Suppressors of cytokine signaling (SOCS) proteins and JAK/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3.
Overexpression of miR -155 promotes proliferation and invasion of human laryngeal squamous cell carcinoma via targeting SOCS1 and STAT3.
For example, CIS, SOCS1, SOCS2, and SOCS3 have relatively short (50-80 residues) N-terminal regions, whereas SOCS4, SOCS5, SOCS6 and SOCS7 have longer N-terminal regions of up to 380 residues [22, 25, 26].
[5] Genes: PDCD4, programmed cell death 4 (neoplastic transformation inhibitor); TPM1, tropomyosin 1 (alpha); PTEN, phosphatase and tensin homolog; TIMP3, TIMP metallopeptidase inhibitor 3; SOCS1, suppressor of cytokine signaling 1; ZBTB10, zinc finger and BTB domain containing 10; RHOC, ras homolog gene family, member C; CD44, CD44 molecule (Indian blood group);BRMS1, breast cancer metastasis suppressor 1; SOX4, SRY (sex determining region Y)-box 4; TNC, tenascin C; CDC42, cell division cycle 42 (GTP binding protein, 25kDa); CXCR4, chemokine (C-X-C motif) receptor 4; CYP19A1, cytochrome P450, family 19, subfamily A, polypeptide 1.
Researchers from the Universite de Montreal and the Universite de Sherbrooke have found that the SOCS1 molecule prevents the cancer-causing activity of cytokines, hormones that are culprits in cancer-prone chronic inflammation diseases such as Crohns, in smokers and people exposed to asbestos.
En la especie humana se conocen 7 miembros diferentes de la familia SOCS y 4 miembros de la familia PIAS de los cuales con el sistema LIF se han ligado claramente, solo SOCS1, SOCS2 y SOCS3.
These genes include protein kinases (AKT, MEK1, PIM3), growth factors (VEGF, PLGF), GTPases (RHOC, RAB11A, DEXRAS1), cytokine signaling proteins (MCP1, SOCS1, SOCS3, WSB1, IL17R), and a Wnt signaling factor (WNT4).
A recent study reported that DF-1 cells express higher level of suppressor of cytokine signaling 1 (chSOCS1), a negative regulator of cytokine signaling in mammals, than chicken embryonic fibroblast cells, suggesting the dampened signaling activity of DF-1 cells in IFN-alpha (IFN-a) signaling pathways through SOCS1 by inhibiting Janus kinase (JAK)-signal transducers and activator of transcription (STAT) signaling axes [24].