Als

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Related to SOD1: SOD2, SOD3, G93A

Als

(äls), Ger. Alsen, island, 121 sq mi (313 sq km), Sønderjylland co., S Denmark, in the Lille Bælt, separated from the mainland by the narrow Alensund. Sønderborg (partly situated on the mainland) is the main city; other towns include Augustenborg and Nordborg. Farming (particularly of apples and grain), fishing, dairying, and manufacturing (especially of motor vehicle parts) are the main occupations. Danfoss, a company that produces heating and refrigerating plants is there. Its beautiful beaches make the island a popular tourist attraction. It was held by Germany from 1864 to 1920.

ALS

Abbr. for “American Lumber Standards.”
References in periodicals archive ?
It has been suggested that the excess of genetic information in DS patients is the cause of an increase in the activity of SOD1 in these patients (6, 7).
In addition, recent studies have suggested that the accumulation of mutant forms of SOD1 is linked to most sporadic cases of ALS.
MLST, performed using 8 unlinked genes from 6 randomly chosen strains, showed identical sequences for the CAPIO, GPD, LAC1, PLB1, SOD1, IGSI, TEF1, and URE1 genes.
On the contrary, overexpression of SOD1, SOD2 and CTT1 (cytosolic catalase T) at various combinations increased S.
Expression of SOD1 and the Cu-binding protein ceruloplasmin was increased in arsenic-exposed liver and in arsenic-induced liver tumors in the present work.
The work focuses on delivery to the spinal cord and brain to silence the SOD1 gene in ALS, and completion of the project is expected to generate supportive data for clinical development of anti-SOD1 sd-rxRNA therapy.
Total SOD activity includes the activity of two SOD isoforms - SOD1 (Cu/ZnSOD) citoplasmatic and SOD2 (MnSOD) mitochondrial isoforms.
Pipeline candidates fall under major therapeutic classes such as glutamate receptor antagonists, SOD1 protein folding stabilizers, stem cell therapy, Sodium channel blockers, Interleukin-2 (IL-2) inhibitors, immunomodulators, dopamine antagonists, cell protectants, antioxidants, antibiotics and free radical scavengers.
Palmitoylation of SOD1 and the pathogenesis of ALS Principal Investigators: Raymond Roos, M.
Postischemic recovery of contractile function is impaired in SOD2 ([+ or -]) but not SOD1 ([+ or -]) mouse hearts.
Key classes of mechanism of action include SOD1 protein folding stabilizers, dopamine agonists, immunomodulators and antioxidants.
Collaboration to Explore Recombinant Human-Derived Monoclonal Antibodies Targeting Misfolded SOD1