Albert Bruce Sabin

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Sabin, Albert Bruce

(sā`bĭn), 1906–93, American physician and microbiologist, b. Bialystock, Russia, grad. New York Univ. (B.S., 1928; M.D., 1931). He emigrated to the United States in 1921 and was naturalized in 1930. He conducted medical research for several organizations before joining (1939) the faculty at the Univ. of Cincinnati college of medicine; there he became (1946) professor of research pediatrics. He conducted research on viral and other infectious diseases and developed (c.1959) a live-virus vaccine for immunization against poliomyelitispoliomyelitis
, polio,
or infantile paralysis,
acute viral infection, mainly of children but also affecting older persons. Historically, there were three immunologic types of poliomyelitis virus, but two of three types of the wild virus have been eradicated;
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. The Sabin vaccine may be taken orally and provides longer immunity than the killed-virus vaccine. Also, the killed-virus vaccine protects only against paralysis, whereas the live vaccine guards against both paralysis and infection.
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References in periodicals archive ?
Serumlarda seropozitiflik, Sabin-Feldman Dye Test (SFDT) ve Indirekt Hemaglutinasyon (IHA) testi ile saptanmistir.
Samples continuing to yield equivocal IgG results should be tested by other methods, such as Western blot or the Sabin-Feldman dye test. If equivocal results are obtained by ECLIA, the use of other automated assays for confirmation is not appropriate, because their relatively low sensitivity may lead clinicians to incorrectly consider many patients to be uninfected.
By Sabin-Feldman dye test and indirect hemagglutination test, seropositivity was observed in quails infected with [10.sup.5] and [10.sup.4] tachyzoites.