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(organic chemistry)
C6H4OHCHO Clear to dark-red oily liquid, with burning taste and almond aroma; soluble in alcohol, benzene, and ether, very slightly soluble in water; boils at 196°C; used in analytical chemistry, in perfumery, and for synthesis of chemicals. Also known as helicin.



(o-hydroxybenzaldehyde), a colorless liquid with a bitter almond odor and a burning taste. Boiling point, 196.8°C; density, 1.167 g/cm3 at 20°C. Salicylaldehyde is miscible in all proportions with ethanol and ether and is readily soluble in benzene.

Salicylaldehyde is found in shrubs of the genus Spiraea. It is usually produced from phenol by the action of chloroform in the presence of an alkali base. It is used in the production of coumarin, saligenin, and salicylaldoxime (an important analytical reagent), and also in analytical chemistry—for example, to detect hydrazine.

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Zhang, Synthesis, characteristic and theoretical investigation of the structure, electronic properties and second-order nonlinearity of salicylaldehyde Schiff base and their derivatives, Spectrochimica Acta Part A, 78, 449 (2011).
The Schiff base ligand (L) is formed in good yield by the condensation of the 2,6-diamino pyridine and 5-bromo salicylaldehyde at ethanol under refluxing [33, 34] (Scheme 1).
Metal chelates of the Schiff bases derived from salicylaldehyde and amino acids have been shown to an important class of compounds in elucidating the mechanism of transamination reaction in biological systems (Chohan et al., 1997).
Jasinski, "Synthesis, structures, spectroscopy and antimicrobial properties of complexes of copper(II) with salicylaldehyde N-substituted thiosemicarbazones and 2,2'-bipyridine or 1,10-phenanthroline," European Journal of Medicinal Chemistry, vol.
We also identified malonohydrazide as reaction product besides salicylaldehyde azine upon the reaction of ethyl 2-oxo-2H-chromene-3-carboxylate with hydrazine hydrate [43].
Sodium oleate (CP), n-Hexane (AR, 97%), ammonia solution (AR), and salicylaldehyde were obtained from Shanghai Aladdin Chemistry Co.
The cobalt (Co) complexes with the Schiff bases derived from salicylaldehyde and its analogues have been extensively studied (9).
There are evidences confirming that salicylaldehyde Schiff bases, obtained from the condensation of the salicylaldehyde and its derivatives in alkaline grind solution [8, 9], showed abetter carrying oxygen ability and catalysis of mimic enzymes due to their structure similar to the porphyrin and phthalocyanine rings, which displayed a great anticancer, anti-inflammatory, antibacterial, and antiviral activity.
Cadmium acetate dihydrate, 2hydroxy-1- naphthaldehyde, salicylaldehyde, hexadecylamine (HDA), ethanol, acetone, and toluene were reagents purchased from Sigma-Aldrich and were all used without further purification.
Simunek, "Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autoxidation and cardiotoxicity," Free Radical Biology & Medicine, vol.
Expression, purification and preliminary crystallographic studies of NahF, a salicylaldehyde dehydrogenase from Pseudomonas putida G7 involved in naphthalene degradation.