86% decrease in mean schistocyte
count, with schistocytes
disappearing in one patient
The peripheral blood smear can show up to 10% schistocytes
, along with helmet cells, which are produced due to damage of the endothelial layer of small vessels, resulting in fibrin deposition and platelet aggregation.
The blood film showed schistocytes
and fragmented red cells and a diagnosis of TTP was first considered.
3%; platelet count of 30 pL; schistocytes
on the blood smear; total bilirubin of 14.
Review of peripheral blood smear revealed markedly increased eosinophils and 4+ schistocytes
on a peripheral blood smear indicate microangiopathic hemolysis.
Nonspecific red blood cell abnormalities can be present, such as anisocytosis, poikilocytosis, anisochromia, basophilic stippling, schistocytes
, and erythrocytes that are poorly hemoglobinized.
While there is a theoretical risk of hemolysis with vortexing, neither study commented on the presence of increased numbers of schistocytes
in post-vortex smear samples.
Abdominal pain, diarrhea, severely decreased platelet count, and schistocytes
on peripheral smear
, burr cells, helmet cells, or red cell fragments); 2) platelet count <150,000/[mm.
On the following three days, acute renal failure, peripheral disseminated intravascular coagulation-related thrombocytopenia and haemolytic anemia with schistocytes
were suggestive of thrombotic microangiopathy.
A peripheral smear showed schistocytes
, anisocytosis and polychromasia suggesting microangiopathic hemolytic anemia.