Scleroma


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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Scleroma

 

a chronic infectious disease of the human respiratory tract. The causative agent is the Frisch-Volkovich bacillus, named for the Austrian bacteriologist A. R. von Frisch, who discovered it in 1882, and the Russian scientist N. M. Volkovich, who isolated a pure culture of the bacteria in 1888. The bacillus enters the nasal mucosa and then the larynx and trachea, giving rise to the formation of thick infiltrates. The initial stages of scleroma are marked by dryness in the nose and the formation of crusts. Affectation of the larynx results in persistent hoarseness; breathing gradually becomes more difficult owing to the increase of the infiltrates. The nasal cavity may become obstructed, and the lumina of the larynx and trachea severely constricted. It is not known how infection with scleroma takes place; direct transmission from one person to another has not been established. There is no specific treatment. Antibiotics and X-ray therapy yield favorable results.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Problems of the epidemiology of scleroma, 2: some aspects of the problem of endemic focus formation.
Scleroma (Rhinoscleroma) a histologic, immunohisto chemical study with bacteriologic correlates.
Association of HLADQA1* 03011-DQB1*0301 haplotype with the development of respiratory scleroma. Otolaryngol Head Neck Surg.
pneumoniae rhinoescleromatis is the etiological agent of rhinoscleroma or scleroma infection which is characterized by a granulomatous and chronic process of insidious evolution that affects the mucosa from the upper respiratory tract and might lead to bone invasion and airway obstruction.
Laryngeal involvement may occur in almost half of the cases and hence the disease is also known as respiratory scleroma. Mikulicz established the non-neoplastic inflammatory nature of the disease.
Common causes of laryngeal stenosis include trauma, tracheostomy, partial laryngectomy, granulomatous diseases like TB, Scleroma, Wagener's granulomatosis etc.
Scleroma of the upper respiratory passages: a CT study.