second messenger

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second messenger

[′sek·ənd ′mes·ən·jər]
(cell and molecular biology)
Any small molecule or ion that occurs in the cytoplasm of a cell, is generated in response to a hormone binding to a cell-surface receptor, and activates various kinases that regulate the activities of other enzymes.
References in periodicals archive ?
One drug which we know directly affects the second messenger system is lithium, which directly affects activation of protein kinase C, which in turn activates protein synthesis of .
His text includes a discussion on the extracellular activity of neurons, and, briefly, on their intracellular functions, known as the second messenger system.
We are particularly interested in the signaling cascade that utilizes the phospholipase C b4 (PLCb4) second messenger system.
mediated second messenger system causes saliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glands.