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A seven-carbon ketose sugar widely distributed in plants of the Crassulaceae family; a significant intermediary compound in the cyclic regeneration ofD-ribulose.



(also sedoheptose), C7Hl4O7, a monosaccharide of the ketoheptose group. Sedoheptulose exists in the optically active D-and L-forms and also occurs as the racemate. The D-form is widely distributed in nature. Sedoheptulose takes part in the biosynthesis of monosaccharides in the leaves of green plants during photosynthesis and in carbohydrate metabolism in animal organisms (pentose-phosphate cycle).

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We developed a sensitive liquid chromatography-tandem mass spectrometry (LC-MS/ MS) method to simultaneously analyze the intracellular sugar phosphates dihydroxyacetone phosphate (DHAP), glyceraldehyde 3-phosphate, erythrose 4-phosphate, ribose 5-phosphate, ribulose 5-phosphate, xylulose 5-phosphate, fructose 6-phosphate, glucose 6-phosphate, and sedoheptulose 7-phosphate in blood spots.
The measurement of xylulose 5-phosphate, ribulose 5-phosphate, and combined sedoheptulose 7-phosphate and ribose 5-phosphate in liver tissue.