SeMet was the major compound identified in the gastrointestinal extract while SeMet selenoxide
was its main degradation product formed after medium and long-term sample storage, respectively.
Allison, "Activation energies of selenoxide
elimination from Se-substituted selenocysteine," Journal of Molecular Modeling, vol.
For example, free-SeMet may be more susceptible to oxidation (which then converts to selenomethionine selenoxide
) than it is within a protein, due to some sort of protection because of the tertiary-folding of the protein itself.
It is only after four in situ chemical transformations (oxidation to the selenoxide
, [2,3]-sigmatropic rearrangement, a second oxidation and loss of allyl alcohol) that the true catalyst (4) is generated (equation 1).
Stoffregen University of Photochemistry of aromatic Wisconsin-River sulfoxides and Falls selenoxides
Our consortium's most important activity is an annual regional undergraduate research (UR) conference focused on oral and poster research presentations by our students.