Hansell et al., "Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone
inhibitors of the trypanosomal cysteine protease cruzain," Journal of Medicinal Chemistry, vol.
(ii) 4-[N-(3:4-methylene dioxy benzylidene) amino] antipyrine semicarbazone
Therefore, it is likely that the pharmacophoric descriptors in arylsemicarbazones are thought to be a hydrogen bonding semicarbazone
group and a lipophilic aryl ring which align at their complementary areas on the macromolecular complex in vivo .
Dihydro-LH-imidazo [1,5-b]pyrazole-4,6(2H,5H)-dione 119 was synthesized from treatment 1-(benzylideneamino)-5-(2-hydroxyethyl)hydantoin 117, prepared from treated sodium salt of acetone semicarbazone
115 with a-bromo-y-butyrolactone 116 and the reaction mixture was then subjected to acid hydrolysis followed by condensation with benzaldehyde, with SO[Cl.sub.2] to give 1-benzylidene-2,3,3a,4,5,6-hexahydro-4,6-dioxo-1H-imidazo[1,5-b]pyrazolium chloride 118.
A series of eight new thiosemicarbazones and semicarbazone
compounds synthesized from a formyl chromone backbone in our laboratory will be discussed.
The present work is related to the preparation and characterization of Nickel (II) complexes of semicarbazone
and thiosemicarbazone of anisaldehyde.
Stability of pyridoxal-5'phosphate semicarbazone
: applications in plasma vitamin [B.sub.6] analysis and population surveys of vitamin [B.sub.6] nutritional status.
Jesmin, In vivo Anticancer activity of vaniline semicarbazone
. Asian Pecific J.
Paul, "Corrosion inhibition investigations of 3-acetylpyridine semicarbazone
on carbon steel in hydrochloric acid medium," Research on Chemical Intermediates, vol.
Powell, "Synthesis, characterization and in vitro anti-cancer activities of semicarbazone
and thiosemicarbazone derivatives of salicylaldehyde and their copper complexes against human breast cancer cell line MCF-7" Indian Journal of Chemistry A, vol.
PLP and PL in blood were measured as their semicarbazone
derivatives, pyridoxal 5'-phosphate semicarbazone
(PLPSC) and pyridoxal semicarbazone
(PLSC), respectively (12,13).