antagonist

(redirected from Serotonin antagonist)
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Related to Serotonin antagonist: Serotonin syndrome, Dopamine antagonist

antagonist

1. any muscle that opposes the action of another
2. a drug that counteracts the effects of another drug

antagonist

[an′tag·ə‚nist]
(biochemistry)
A molecule that bears sufficient structural similarity to a second molecule to compete with that molecule for binding sites on a third molecule.
(pharmacology)
A drug or other chemical substance capable of reducing the physiological activity of another chemical substance; refers especially to a drug that opposes the action of a drug or other chemical substance on the nervous system by combining with and blocking the nerve receptor.
(physiology)
A muscle that contracts with, and limits the action of, another muscle, called an agonist, with which it is paired.
References in periodicals archive ?
3] receptor antagonists or serotonin antagonists suppress nausea and vomiting by inhibiting serotonin binding to the 5-[HT.
The norepinephrine and specific serotonin antagonist, Remeron (mirtazapine), is reported to be subjectively sedating.
Palonosetron is a selective and potent serotonin antagonist that associated to the chemotherapy of solid tumours has demonstrated improved efficacy compared to older 5-HT3 receptor antagonists.
officinale extract could be acting either as an inhibitor of mast cell degranulation or as a serotonin antagonist.
However, an antidepressant with a novel mechanism of action has huge commercial potential and the most promising candidate to date is Servier and Novartis's melatonin agonist and serotonin antagonist Valdoxan (agomelatine).
Serotonin receptor antagonists are the most prevalent drug clasWe predict that serotonin antagonist companies will be important players in the market in the future, led by Sanofi-Aventis eplivanserin.
Trazodone is a serotonin antagonist reuptake inhibitor with proven efficacy as an antidepressant.

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