Sertoli cell

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Related to Sertoli cells: Leydig cells, Leydig

Sertoli cell

[sər′tō·lē ‚sel]
(histology)
One of the sustentacular cells of the seminiferous tubules.
References in periodicals archive ?
These observations suggest that the Aqp1ab, -7, and -10b channels may mediate fluid movement during cell volume reductions and the passage of nutritive molecules from Sertoli cells.
Large cell calcifying Sertoli cell tumor of the testis: comparative immunohistochemical study with Leydig cell tumor.
It has been found that the mass of the Sertoli cells increases to constitute 85-95% of the seminefous tubules (16).
In the second step the cells acquired the capability to attract each other to form aggregates as seen in vivo between embryonic Sertoli cells and germ cells.
The effect of hypothyroidism on Sertoli cell proliferation and differentiation and hormone levels during testicular development in the rat.
sperm cells) and Sertoli cells (responsible for the secretion of androgen binding protein, inhibin, sulfated glycoprotein-2 and transferrin).
Androgen regulation of stage-dependent cyclin D2 expression in Sertoli cells suggests a role in modulating androgen action on spermatogenesis.
The researchers have been investigating how Sertoli cells switch from a multiplying state, making the testis big enough to make sperm, to a mature state that sustains sperm production.
The TD treated animals were presented with degeneration of tubules to mild degree of vacuolation with or without spermatogenesis, degeneration of sertoli cells indicated by aggregation at one end of tubules.
With the purpose of evaluating the efficiency of spermatogenesis and the Sertoli cells, the ratios were calculated between the corrected numbers of the cells of the spermatogenic lineage and these numbers and the number of Sertoli cells.
The Sertoli cells are tightly aligned around the tubule, forming a barrier between the outside and inside of the tubule, and creating a narrow lumen.
Complete deletions of AZFb and AZFb+c are characterized by a histological picture of Sertoli cell only (SCO) or spermatogenic arrest resulting in azoospermia (9) and deletions in AZFa region have been associated with SCO I (complete absence of germ cells in the seminiferous tubules and presence of Sertoli cells only) syndrome (10,11).