Sertoli cell

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Related to Sertoli cells: Leydig cells, Leydig

Sertoli cell

[sər′tō·lē ‚sel]
(histology)
One of the sustentacular cells of the seminiferous tubules.
References in periodicals archive ?
There are numerous extensive reports on the description of the Leydig cells and Sertoli cells and their function in different animal groups (Camatini et al.
Conclusion: This study introduced and applied a method to isolate, culture, and purify human sertoli cells with high purity which made possible further researches on these cells.
Sertoli cells are the major component of blood-testis barrier; its main function is to nourish the developing sperm cells through the stages of spermatogenesis and secret many bioactive factors to affect spermatogenesis.
Testosterone is converted to estradiol-17p by the aromatase complex in Sertoli cells in immature rats (not in Leydig cells as in adults) (Cheng and Mruk, 2012).
Transduction of Sertoli cells with adenoviral and lentiviral vectors carrying the mouse Steel gene has been found to restore spermatogenesis (30,35).
The study showed that the treatment with the drug Dacarbazine for five consecutive days resulted histological changes with serious damage in the testicles of male rat, where the disintegration and spacing of seminiferous tubules was noted in an abnormal form, sloughed epithelial germ cells for this tubules, a decrease in testicular content for each spermatozoa and spermatocytes with the occurrence of morphological abnormalities of these cells, laceration of links between Sertoli cells and spermatocytes which is next to it and lack in the number of Leydig cells that are taken irregular shapes.
Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse Sertoli cells, evidence of binding at the COX2 active site, and implications for endocrine disruption.
In Control animals, vimentin surrounded the nucleus and showed apical extensions in a "spoke-like" pattern in Sertoli cells from Control mice as previously observed [30].
Water efflux from the Sertoli cells of the germinal epithelium and from germ cells controls the seminiferous tubule fluid to create a suitable environment for spermatogenesis (Russell et al.
The histopathologic diagnosis in this bird was a Sertoli cell tumor with splenic metastasis.