Serum Hepatitis


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Related to Serum Hepatitis: hepatitis B, infectious hepatitis

serum hepatitis

[′sir·əm ‚hep·ə′tīd·əs]
(medicine)
A form of viral hepatitis transmitted by parenteral injection of human blood or blood products contaminated with the type B virus.

Hepatitis, Serum

 

an infectious disease of man; a form of viral hepatitis. The causative agent is a type B virus, and the source of infection is a person infected with the icteric or anicteric form of the disease, or a carrier of the virus. The virus appears in the blood three to four weeks before the appearance of symptoms and remains there for several months and sometimes several years after recovery.

Serum hepatitis is transmitted by transfusions of blood, plasma, serum, or preparations made from them and occasionally by poorly sterilized syringes or needles during inoculations, tests for intracutaneous reactions, stomatological examinations, the drawing of blood, or the injection of medicines.

The incubation period of serum hepatitis ranges from 60 to 160 days. Clinical manifestations and treatment are the same as for infectious hepatitis. Important diagnostic methods are blood transfusion or medical examination performed two or more months before the onset, and testing for the existence of the Australia antigen in the blood.

Serum hepatitis is prevented by medical and laboratory testing of blood donors and by observing standard rules for the sterilization and use of medical instruments.

REFERENCE

Butiagina, A. P. Syvorotochnyi gepatit. Moscow, 1962.
References in periodicals archive ?
Serum hepatitis associated with commercial plasma transfusion in horses.
After 52 weeks in the pediatric study, 23% of those on lamivudine had a loss of serum hepatitis B e antigen and a reduction in HBV DNA to below detectable levels, vs.
* Hepatitis B-formerly called serum hepatitis, is the most serious form of hepatitis, with over 200 million carriers in the world and an estimated one million in the United States.
Hepatitis B, formerly called serum hepatitis. The incidence of this viral infection has not declined significantly in the U.S.
Hepatitis B, formerly called serum hepatitis, is usually transmitted by blood or blood products infected with the B virus.
Second type transmitted parenterally was called serum hepatitis, later termed type B hepatitis.
Eighty-seven patients with chronic hepatitis B, who were diagnosed by positive serologic tests for serum hepatitis B surface antigen for at least 6 months, were all from Affiliated Hospital of Nantong University, including 49 men and 38 women, median age (25th percentile; 75th percentile) 38.4 (34.1; 49.9).
Patients in the 10-mg and 30-mg groups had significantly greater decreases in serum hepatitis B virus (HBV) DNA levels at week 48; 21% of the 10-mg and 39% of the 30-mg patients had undetectable serum HBV DNA levels, compared with none of the placebo patients (N.
Quantitative assessment of serum hepatitis B e antigen, IgM hepatitis B core antibody and HBV DNA in monitoring the response to treatment in patients with chronic hepatitis B.
Over the next century viral hepatitis was classified into two diagnostic categories- one infectious hepatitis and another serum hepatitis. Later on the names 'Hepatitis A' and 'hepatitis B' for serum hepatitis were proposed (Mac Callum, 1947).

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