Serum Hepatitis

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Related to Serum Hepatitis: hepatitis B, infectious hepatitis

serum hepatitis

[′sir·əm ‚hep·ə′tīd·əs]
A form of viral hepatitis transmitted by parenteral injection of human blood or blood products contaminated with the type B virus.

Hepatitis, Serum


an infectious disease of man; a form of viral hepatitis. The causative agent is a type B virus, and the source of infection is a person infected with the icteric or anicteric form of the disease, or a carrier of the virus. The virus appears in the blood three to four weeks before the appearance of symptoms and remains there for several months and sometimes several years after recovery.

Serum hepatitis is transmitted by transfusions of blood, plasma, serum, or preparations made from them and occasionally by poorly sterilized syringes or needles during inoculations, tests for intracutaneous reactions, stomatological examinations, the drawing of blood, or the injection of medicines.

The incubation period of serum hepatitis ranges from 60 to 160 days. Clinical manifestations and treatment are the same as for infectious hepatitis. Important diagnostic methods are blood transfusion or medical examination performed two or more months before the onset, and testing for the existence of the Australia antigen in the blood.

Serum hepatitis is prevented by medical and laboratory testing of blood donors and by observing standard rules for the sterilization and use of medical instruments.


Butiagina, A. P. Syvorotochnyi gepatit. Moscow, 1962.
References in periodicals archive ?
Significance of early measurement of serum hepatitis C virus RNA in predicting response to interferon therapy in patients with chronic hepatitis C.
Comparison of serum hepatitis C virus RNA concentration by branched DNA probe assay with competitive reverse transcription polymerase chain reaction as a predictor of response to interferon-alpha therapy in chronic hepatitis C patients.
Hepatitis C virus genotypes and quantitation of serum hepatitis C virus in liver transplant recipients: relationship with severity of histological recurrence and implication in the pathogenesis of HCV infection.
Sustained virological response was defined as undetectable serum hepatitis C RNA levels post-treatment (on or after study week 68).
These results demonstrate that treatment with adefovir dipivoxil as monotherapy or in combination with lamivudine was associated with significant reductions in both serum hepatitis B virus (HBV) DNA and alanine transaminase (ALT, a measure of liver damage) levels through 16 weeks in patients infected with lamivudine-resistant HBV.
Study results show that 48 weeks of treatment with adefovir dipivoxil was associated with improved liver histology and reduced serum hepatitis B virus (HBV) DNA concentration (a marker of viral replication) in patients infected with the precore mutant strain of the virus.
A key variable measured by the study was sustained viral response, defined as undetectable serum hepatitis C RNA after the treatment-free follow-up period.

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