33% ) in our study next to sex cord
stromal tumors (SCSTs) (3/300 or 1%).
Testicular tumors can be broadly classified into GCT, sex cord
stromal tumors, mixed germ cell-sex cord
stromal tumors, and miscellaneous tumors.
Distribution of neoplastic lesions based on cell of origin showed 90% of tumours arising from surface epithelium, 6% of tumours from germ cell and 4% of tumours from sex cord
This descriptive study was carried out at Pathology Department, Shifa International Hospital from 2007 to 2016; all sex cord
stromal tumours diagnosed during this time period were included.
Table 1: Morphological classification of ovarian neoplasms Sest Germ cell Sex cord
stromal Metastatic Serous Teratoma: Granulosa cell Krukernberg/drop Mature/ immature Mucinous Dysgerminoma Fibrous tumor Loco-regional metastasis Endometrioid Endodermal sinus sclerosing stromal cell (yolk sac) cell Clear cell Choriocarcinoma sertoli-stromal cell (leydig) Brenner Embryonal cell Steroid cell Undifferentiated Struma ovarii
The histopathology classifications of ovarian tumors included surface epithelial-stromal, sex cord
stromal, and germ cell tumors.
Postoperative paraffin pathology found a mixed germ cell tumor (GCT) composed of immature teratoma, dysgerminoma [Figure 1], and yolk sac tumor [Figure 2] in right ovary while a mixed tumor composed of GCT and sex cord
stromal tumor (mature teratoma and gonadoblastoma) was identified in left ovary.
Testicular tumors are divided into two categories: germ cell tumors and nongerm cell tumors derived from stroma and sex cord
commonly known as sex cord
Granulosa cell tumors arise from ovarian sex cords
and make up an estimated 1% of all ovarian cancer cases but comprise more than 70% of all sex cord
48%) in the sex cord
stromal group and 4 tumours (6.
GCTs are rare sex cord
stromal tumours of the ovary, made up of granulosa cells (sex cord
) and stromal cells (thecal cells or fibroblasts).
Regarding the analysis of 20 undifferentiated or poorly differentiated tumors, sex cord
tumors with 7 cases were found as the commonest malignancy.