tuberous sclerosis

(redirected from Shagreen patches)
Also found in: Dictionary, Thesaurus, Medical, Legal.

tuberous sclerosis

[′tü·bə·rəs sklə′rō·səs]
(medicine)
A familial neurocutaneous syndrome characterized in its complete form by epilepsy, adenoma sebaceum, and mental deficiency, and pathologically by nodular sclerosis of the cerebral cortex. Also known as Bourneville's disease.
Mentioned in ?
References in periodicals archive ?
On one hand, the three patients had almost the same major features of TSC and the shagreen patches of the proband and his brother was nearly at the same position on the back.
More obvious lesions such as angiofibromas or shagreen patches usually appear in childhood to early adolescence.
There were numerous adenoma sebaseum on her face (Fig-1), periungual fibromas (without trauma anamnesis) around the toenails (Fig-2), forehead plaques (Fig-3), Shagreen patches around the lumbar region, hypomelanotic macules on the back.