Sham Feeding


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Sham Feeding

 

a method proposed by I. P. Pavlov in 1890 for investigating the role of the central nervous system in the regulation of gastric secretion; this method is also useful in studying other problems in neurophysiology, such as the blood glucose level, the state of food depots, and the distribution of water in the body when swallowed food or water do not enter the gastrointestinal tract.

Sham feeding, like sham drinking, consists in the swallowing of food (or liquid) by an animal whose esophagus has been surgically severed and its ends drawn out to the neck and healed into the skin (such a chronic operation is called an esophagotomy). The experiment is usually performed on a dog, to which a gastric fistula is first applied. Within a few minutes after the beginning of sham feeding, gastric juice begins to flow, secretion of which does not cease for 2–3 hours, even when the sham feeding is short. If sham feeding continues for several hours, one may obtain from the dog up to 1 liter of pure (that is, unmixed with food) gastric juice, which is used for therapeutic purposes.

As I. P. Pavlov and his associates demonstrated, when the vagus nerves—which convey central nervous system impulses to the stomach—are bilaterally severed, secretion of gastric juice during sham feeding is absent. This confirms the reflex nature of the first phase of gastric juice secretion, during which approximately one-fourth of the normal quantity of gastric juice (the so-called initiative juice) is secreted.

REFERENCE

Pavlov, I. P. Polnoe sobranie sochinenii, vol. 5. Moscow-Leningrad, 1952.

O. M. BENIUMOV

References in periodicals archive ?
2008), was intraruminally infused to replenish saliva lost from the esophageal fistula during sham feeding.
The esophageal fistulae of goats were always closed by the esophageal fistula plugs (Figure 1C and D) except when sham feeding experiments were conducted.
In the first experimental stage, group A was the control and was subjected to the intraruminal infusion of artificial parotid saliva under sham feeding conditions (SFC) while group B as the treatment maintained under normal feeding conditions (NFC).
2008), was intraruminally infused to replenish saliva removed from the esophageal fistula during sham feeding.
Previous research has suggested that sham feeding can enhance bowel function by increasing gastric motility and hormone secretion, and one small Japanese study has linked gum chewing to early recovery from postoperative ileus after laparoscopic colectomy (J.
2010) has found that in sham feeding conditions in which swallowed boluses of dry forage intake and secreted saliva were prevented from entering the rumen by removal via an esophageal fistula, eating rates were remained at high levels even after 40 min of feeding period had elapsed in large-type esophageal-fistulated goats fed dry forage twice daily.
In the present study, experiments were conducted under sham feeding conditions whereby esophageal boluses were removed during feeding to prevent them from entering the rumen.
In this study, two experiments under sham feeding conditions were conducted to determine whether or not ruminal distension brought about by feed boluses (a mixture of secreted saliva and consumed feed) entering the rumen is a factor in the marked suppression of feed intake after 40 min of feeding.
Experiment 1 : The effect of intraruminal insertion of a balloon on dry forage intake in large-type goats during sham feeding : The 5 esophageal- and ruminal-fistulated goats were divided into two groups of three and two animals each.
In the first experiment, group A was the control and maintained under the normal feeding conditions (NFC) while group B was subjected to the sham feeding conditions (SFC).
The effect of sham feeding conditions (SFC) on rate of bolus output, cumulative bolus output, rate of salivary secretion and cumulative salivary secretion Time after Rate of bolus Cumulative feeding output (g/10 bolus output beginning min) (g) (min) 10 1,096 [+ or -] 117.