sickle-cell disease

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sickle-cell disease

[′sik·əl ¦sel di‚zēz]
(medicine)
References in periodicals archive ?
He and other sickle-cell patients will tell you that the worst part of the disease is the debilitating pain.
That is, you have to carry a copy of an abnormal gene from each of your parents to have sickle-cell anaemia.
His research has found that when sickle-cell patients ask for medication-especially opioids to control their pain--they are routinely dismissed as pill seekers, even though they are no more likely to be addicted to painkillers than the general population.
Sickle-cell trait as a risk factor for sudden death in physical training.
A preliminary study of sickle-cell patients with pulmonary hypertension suggests that they can benefit from sildenafil, a blood vessel dilator marketed as the impotence drug Viagra by the New York--based drug company Pfizer.
Using his "designer" mice, Townes plans to test, treatments to relieve or even cure sickle-cell disease.
Can you describe your meeting with a Nigerian delegation in search of a sickle-cell anemia drug that turned things around for you?
People with sickle-cell disease make elongated versions of hemoglobin, the protein in red blood cells that totes oxygen.
If S% is greater than A%, then the smaller 'A' has come from a beta-Thalassaemia gene, and the patient has sickle-cell beta-Thalassaemia (Ache/Ache), not sickle cell trait.
Stem cell transplants have long been a therapy option for children with life-threatening cases of sickle-cell disease, but the procedure itself can be deadly.
By installing a designer gene that offsets the adverse effects of faulty DNA, scientists have prevented sickle-cell disease in mice.
There are simply so many ways it might work that there's a growing excitement about using nitric oxide for sickle-cell disease," Gladwin says.