A growing number of studies have sought to define mitochondrial adaptations in aging skeletal muscle
following various exercise regimens.
is a dynamic organ which is involved primarily in locomotion, generation of body heat and also in maintenance of metabolic homeostasis.8,17 Myokines exert effects on various organs of the body, such as liver, pancreas, bone, hear t, fatty tissue and brain cells.
comprises approximately 40% of total body mass and contains more than 50% of the total body proteins in humans.
Results: Examination of HandE stained sections of the extensor digitorum longus muscle of the control group revealed the histological structure of skeletal muscle
. Cross sectional area of myofibers and number of myofibers were significantly lower in group B as compared to the control group A.
The study titled, "PlanHab: hypoxia does not worsen the impairment of skeletal muscle
oxidative function induced by bed rest alone" was published in the (https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/JP275605) Journal of Physiology on April 17.
sections of 10 [micro]m were fixed with 4% paraformaldehyde and incubated overnight at 4[degrees]C with skeletal myosin primary antibody diluted 1 : 50 (Sigma-Aldrich, St.
"Isn't it rather strange," quipped the skeletal muscle
, "that you
Therefore, the purpose of this study was to investigate a long-term effects of ACL resection on the morphological and contractile properties of skeletal muscles
around the knee joint, namely rectus femoris (RF) and semimembranosus (SM) muscles, among ACL-resected, contralateral and sham-operated sedentary control limbs of rats.
(3) also demonstrated that mice submitted to eccentric and exhaustive aerobic exercise had impaired IRS-1 tyrosine residue phosphorylation and PI3K/Akt signaling in the skeletal muscle
when compared with a control group not submitted to exercise, resulting in decreased GLUT4 translocation to the membrane.
Difference in oxygen uptake in skeletal muscles
between plateau zokor (Myospalax rufescens baileyi) and plateau pika (Ochotona curzoniac).
The most extensively studied isoforms in skeletal muscle
are Pgc-1[alpha]-b, Pgc-1[alpha]-c, Pgc-1[alpha]4, the n-truncated splice variant NT-Pgc-1[alpha], and the full length variant FL-Pgc-1[alpha] [17-19, 21, 23, 24].
In the case of T2DM, this overt hyperglycemia results from the reduced action of insulin on its target tissues, such as skeletal muscle
, liver, and adipose tissue, at least on initial stages [4,8,9].