Smith, Michael

Smith, Michael,

1932–2000, British-born Canadian biochemist, Ph.D. Univ. of Manchester, 1956. Smith was a researcher at the Univ. of British Columbia from 1961 until his death in 2000. He shared the 1993 Nobel Prize in Chemistry with Kary MullisMullis, Kary Banks,
1944–, American biochemist, b. Lenoir, N.C., Ph.D. Univ. of California, Berkeley, 1972. Mullis was a researcher with Cetus Corp., Emeryville, Calif., from 1979 to 1986 and with Xytronyx, Inc., San Diego, Calif., from 1986 to 1987.
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 for their contributions to the development of methods in DNA-based chemistry. Smith was specifically cited for developing a technique known as site-directed mutagenesis, which enables the genetic code to be reprogrammed and specific amino acids to be replaced in proteins. His work paved the way for the construction of proteins having new properties, with such potential applications as antibodies tailored to attack cancer cells and crop strains modified for more rapid growth.
References in periodicals archive ?
Evan Pedone, Marie Smith, Michael Saracusa and Mary Beattie all completed the first of three required courses.
Carl Finnigan, Barrie Smith, Michael Richardson, Matty Pattison and Jamie Holmes all got on the scoresheet as they built on their opening-day victory at Trafford.
The market started to move and suddenly everyone wanted a piece of the action, encouraged no doubt by the fact that Laddies Poker Two was racing for 'the lads' - Derrick Smith, Michael Tabor and John Magnier - and was in the more than capable hands of Jeremy Noseda and John Magnier.
The spirit of international collaboration which drives the work of George Smith, Michael Tompsett, Nobukazu Teranishi and Eric Fossum encapsulates perfectly the ideals of the Queen Elizabeth Prize for Engineering.
Field for this coming Saturday: Tony Barras, Gordon Bradford, Josh Brown, Andrea Buckley, Paul Burke, David Burns, Adam Douglas, Chris Firth, Alan Forrest, Gary Foulkes, Mally Fowler, Frank Griffin, Paul Ingleby, Stuart King, Martin Lally, Brian Lee, Nigel Marshall, Les Oddy, Duncan Reeves, Mark Regan, Tony Riley, Danny Sillitoe, Neil Slattery, Grez Smith, Kieran Smith, Michael Sweeney, Scott Tattersley, Danny Teale, Danny Towning, Garry Walker, Stephen Walker, Wally Whytell, Gary Wike.
Mr Salmond said Iain Duncan Smith, Michael Gove and Boris Johnson were already preparing "an alternative government" in the event of a Leave vote on June 23.
The 13 members of the class of 2016 include Cassidy Bergen, Angel Botello, Jordan Evans, Miranda Goodard, Drew Hamlow, Aren Montes, Madison Phillipak, Taylor Quirk, Annastazia Rauch, Jorden Smith, Michael Stevens and Idgie Williams.
Greg Smith, Michael Tanner, and Zach Lehner (illustrator); JUNIOR BRAVES OF THE APOCALYPSE; Oni Press (Comics & Graphic Novels: Comics & Graphic Novels) 19.
He ripped out the Australian middle order of Steve Smith, Michael Clarke, Adam Voges and Mitchell Marsh in a hostile spell before adding the scalps of Mitchell Johnson and Peter Nevill for figures of six for 79.
LISBURN YOUTH: Eoin Barrett, Luke Sterling, David English, Eoin Smith, Michael Byrne, Cormac Kennedy, Jordan Kennedy, Michael Burns, Choihan Hughes, Michael Close, Neal McParland.
The show features work by more than 50 nationally recognized artists, including Massachusetts-based artists Keri Straka, Steve Murphy, Dawn Dishaw, Warren Smith, Michael McCarthy, Donna McGee, Maya Machin, and more.
Social trends expert Neer Korn said that celebs like Glenn McGrath, Dick Smith, Michael Hussey, Adam Hills and the fictional Dave Rafter were also highlighted as desirable ideals of manhood in the study.