SP1

(redirected from Sp1 transcription factor)
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SP1

(1) (Scalable POWER 1) See IBM SP.

(2) (Service Pack 1) The first service pack introduced to upgrade a major release of software. See service pack.
References in periodicals archive ?
Binding of Sp1 transcription factor was further confirmed by gel shift and ChIP analyses.
Results from promoter assay, electrophoretic mobility shift assay (EMSA) and chromatin-immunoprecipitation (ChIP) assay revealed that Sp1 transcription factor regulates the bovine Nanog proximal promoter activity through direct binding to a Sp1-binding site in the bovine Nanog proximal promoter, whereas NF-[kappa]B, which plays an important role in transcriptional activation of the Nanog expression in both human and murine ESC, is dispensable in the bovine Nanog promoter activity.
After blocking the sections in 5% goat serum and 3% bovine serum in 0.1 M phosphate buffer saline, they were incubated with antibodies against rabbit anti-phosphorylated NF-[kappa]B (p-NF-[kappa]B) and SP1 transcription factor (Santa Cruz Biotechnology, Santa Cruz, CA) at 4[degrees]C overnight.
KLF family members are closely related to Sp1 transcription factors but are distinguished by a unique pattern of three cysteine-2/histidine-2 zinc finger motifs separated by seven conserved amino acids at the carboxy terminal of the proteins [25].