Spike Potential

Also found in: Dictionary, Thesaurus, Medical, Legal.

Potential, Spike


a large and sudden change in electrical potential that accompanies excitation in nerve and muscle cells and fibers. In physiology, the term “spike potential” is often used as a synonym for action potential. In clinical electroencephalography spike potential refers to gross potentials reaching 10 milliseconds in duration that are outwardly similar to the action potential of a nerve. These potentials are detected in an electrocorticogram taken with certain pathological disturbances, particularly epilepsy.

References in periodicals archive ?
The P -1' potential often merged with the spike potential or divided the negative initiation potential into two waves, N -1 and N -1' (see Figure 2, a, b).
But no spike potentials ever appeared, even after termination of a hyperpolarizing DC current injected into the heart muscle (e.