Stanford Moore


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Moore, Stanford

 

Born Sept. 4, 1913, in Chicago. American biochemist. Member of the US National Academy of Sciences and of the American Academy of Arts and Sciences.

Moore graduated from Vanderbilt University in 1935. Beginning in 1939 he worked at the Rockefeller Institute for Medical Research (now Rockefeller University) in New York City, where he became a professor of biochemistry in 1952. From 1950 to 1951, Moore gave a series of lectures at the University of Brussels (Belgium); in 1951 he conducted research at Cambridge University (England). He studied the structure of a number of proteins, primarily the enzyme ribonuclease, and developed the chromatographic technique of chemical analysis. Moore worked with W. Stein on the development of automatic apparatus for the chromatographic separation and quantitative determination of amino acids. In 1972 he was awarded the Nobel Prize for Chemistry (with C. Anfinsen and W. Stein) for his pioneering work in the chemistry of enzymes.

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The ramifications of this automated technique, which was first pioneered by Nobel laureates Stanford Moore and William Stein in 1958, have influenced research in areas ranging from the nutritional analysis of animal feed, to the assurance of quality control in pharmaceuticals, to the detection of human amino acid deficiency disorders.

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