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Histologically, the tumor is characterized by a well-circumscribed nodule of anastomosing epithelial strands and basaloid buds in a myxoid stroma (Figure 1, G and H).
Keratoconus, Keratoglobus, Pellucid marginal degeneration, keratectasia following refractive surgery, Stromal opacities/scars sparing Descemet's membrane and Corneal dystrophies involving anterior/deep stroma.
Although this hypothesis is supported by the fact that similar histologic findings are seen in normal mammary stroma during the luteal phase of the menstrual cycle, the lesion is also seen in men and in women not taking hormone therapy.
18] In our case, we saw classical history given by the patient and presence of endometrial glands and stroma during histopathological examination.
It has been evident that stroma has a prognostic value in esophageal cancer (18,19) and breast cancer (20), especially triple negative breast cancer (21,22).
18 They reported that stroma rich type of PA showing thin capsule or no capsuleand that 97% of all PA showed focal areas of thin capsule.
Discordance between stroma and glandular elements signifies hormonal imbalance.
Although conducted in prostate cell culture, the study highlights a potentially important role of the stroma in other cancers.
There was also adnexal staining, but it was significantly less than what was seen in the peritumoral stroma.
Fluorescein stain aided in diagnosis of corneal ulceration, the dye not only stained the ulcerated area, but also migrated under the loose flaps of epithelium and stained the surrounding anterior stroma and this made ulcers appear larger than actual size (Fig.
In anterior corneal dystrophy, corneal epithelium, basement membrane and superficial corneal stroma are involved.
No reactivity for estrogen receptors, progesterone receptors or smooth muscle actin was noted in the stroma.