hydroxamic acids as potent inhibitors of histone deacetylase (HDAC).
Both 7 and 8 were converted to the corresponding N-hydroxy succinimide
(NHS) esters and then reacted with the peptide units, CP1, CP2, and CP3 that had been prepared by Fmoc solid-phase peptide synthesis, to afford 4-6, respectively.
All the paints were formulated at a stoichiometry of 1:1 with 1 mole of succinimide
and 2 moles of 1,2,4-triazole per mole of catalyst, using TMPTA as the acryloyl, at a part A solids of 92.5% with 30% of the C-H functionality coming from the reactive diluent.
Deamidation of Asn occurs via formation of a cyclic succinimide
intermediate which leads to the conversion of an Asn residue into L or D Asp or L or D iso-Asp.
Synthesis and antimicrobial activity of some of new 1,1,3- trisubstituted cyclobutane-containing thiazoles, succinimide
and phthalimide derivatives.
group of PFD promotes formation of the covalent bonds with primary amino groups (lysine and arginine residues) of histone H1.3 to form the conjugate "Histone H1-PFD" (Figure 2).
To examine the effects of NNAV on cell division, splenocytes were stained with the 5carboxyfluorescein diacetate succinimide
ester (CFSE; eBioscience, San Diego, CA, USA) at the concentration of 2.5 [micro]Mand then incubated for 10 min at room temperature in the dark.
Solution of dextrose (freshly prepared), sodium dodecyl sulfate, triton X-100, and succinimide
(all are S D Fine-Chem Limited, Mumbai, India) was prepared with triple distilled water.
The free carboxylic function was coupled to N-hydroxy succinimide
using only DCC as the catalyst.
(23.) Pugh, RJ, Fowkes, FM, "The Dispersibility and Stability of Coal Particles in Hydrocarbon Media with a Polyisobutene Succinimide
Dispersing Agent." Colloids Surf, 11 423-427 (1984)
In the past decade the interest of transition metal complexes is shifted from using inorganic anions to organic anions and large number of complexes of organic anions such as phthalimide, succinimide
, oxalate, formate, benzoate and phthalate with first transition metals series have been reported [1,2].
The electrodes were then washed with toluene and allowed to react for 2 h with the crosslinking agent, N-[gamma]-maleimidobutyryloxy succinimide
(MD Biosciences, San Diego, CA), which was dissolved in a minimum amount of dimethylformamide and diluted with ethanol to a final concentration of 5 mM.