Sulfonamide (SAs) standards: sulfadiazine (SDZ), sulfadoxine (SDX), sulfamethoxazole (SMZ), and sulfathiazole
(STZ) were all 99.9% (Sigma-Aldrich, Germany); acetonitrile and methanol for LC-MS and dichloromethane for HPLC (Merck Germany); 98-100% formic acid (Sigma-Aldrich, Germany); trichloroacetic acid, p.a., and sodium hydroxide (Penta, Czech Republic); argon (Linde Gas, Germany).
The sulfonamide analytical standards (sulfathiazole
(STZ), sulfamethoxazole (SMX), sulfamerazine (SMR), sulfamethoxypyridazine (SMPD), sulfadimethoxine (SDMX), sulfapyridine (SP), sulfamethazine (SMZ)), and trimethoprim (TMP) were purchased from Sigma-Aldrich Company Ltd.
Ciprofloxacin, chlortetracycline, doxyclocyline, enrofloxacin, epi-chlortetracycline, epi-oxytetracycline, epi-tetracycline, iso-chlortetracycline, lomefloxacin, norfloxacin, ofloxacin, ormetoprim, oxytetracycline, roxityromycin, sarafloxacin, sulfachloropyridazine, sulfadiazine, sulfadimethoxine, sulfamethazine, sulfamethoxazole sulfathiazole
, tetracycline, trimethoprim, and virginiamycin were not detected in any of the samples.
 monitored seven veterinary antibiotics, including chlortetracycline, oxytetracycline, tetracycline, sulfamethazine, sulfamethoxazole, sulfathiazole
, and tylosin, near a manure composting facility in Gangwon Province, Korea.
It is important to note that sulfamethoxazole exhibits a molar octanol-water partition coefficient of 8.222 compared to 1.101 (both at 298.15 K) exhibited by sulfathiazole
, a sulfonamide structurally related to sulfamethizole (Martinez, F.
The history of GMP began in 1941 after nearly 300 people were killed by one's company's sulfathiazole
tablets, a sulfa drug tainted with the sedative, phenobarbital.
Topical therapy included: treatment of 2% alcoholic solution of aniline dyes, and 2% cream sulfathiazole
Tap water tests done by that commission also revealed the presence of caffeine, barbamazepine, codeine, cotinine, dehydronifedipine, diphenhydramine and sulfathiazole
, substances belonging to the class of drugs in the antihistamine and antidepressant families.
They contained a mixture of penicillin and, I'm sure, sulfathiazole
, and we would use them like salt shakers and sprinkle it into the wounds.
Olivieri, "Simultaneous Multivariate Spectrophotometric Analysis of Ear Drops Containing a Ternary Mixture of Antipyrine, Sulfathiazole
, and Rivanol," Anal.
The drug residues found by FSIS included antibiotics such as sulfamethazine, sulfathiazole
, sulfadimethoxine, and penicillin at levels not permitted by FDA.
Greater than 95% of E coli isolates were resistant to penicillin G, ampicillin, cephalothin, and sulfathiazole
; no E coli were resistant to ciprofloxacin.