Only fosfomycin was left as last choice of treatment.23 Regarding sensitivity pattern, in 170 non-[beta]-lactam antimicrobials, polymyxin-B was (83%), colistin (83%) and tigecycline (98%).24 However, isolates of the same microbe (Mm-141 and Mm-234) in our investigations displayed outstanding resistance against twenty-three available antibiotics belonging to cephalosporins, monobactams, quinolones, tetracyclines, [beta]-lactams, aminoglycosides, macrolides, phosphonic acid, penicillins, polypeptides and sulphonamides
classes, including the ones mentioned in the above studies.
Waseem Malik of Alshifa Hospital said use of sulphonamides
in chickens feed was causing respiratory and gastrointestinal infections and affecting children's growth.
He said cooking at a temperature of at least 165deg F may reduce side effects caused by sulphonamides
but it must not be kept open for hours and soon be refrigerated for later consumption.
Lamuka, "Assessment of sulphonamides
and tetracyclines antibiotic residue contaminants in rural and peri urban dairy value chains in Kenya," International Journal of Food Contamination, vol.
Galarini, "Validation of a confirmatory method for determination of sulphonamides
in muscle according to the European Union regulation 2002/657/EC," Journal of Chromatography A, vol.
Clinical expert opinions and conclusions from basic research or animal models are the cornerstone of recommendations, with sulphonamides
being the drug of choice for at least the last six decades [1-4, 11].
Nevertheless, there were only some sulphonamides
and none oxicam type of NSAIDs induced SJS/TEN in this study.
Dapsone and sulphonamides
are the first choice in treatment, with other options including intralesional, topical or oral steroids, niacinamide, tetracycline, colchicine, and chloroquine.
were the first antibiotics used for treating gonorrhoea in the 1940s, but in a matter of years it became resistant to them.
The commonly incriminated drugs causing FDE are allopurinol, barbiturates, benzodiazepines, captopril, clindamycin, carbamazepine, cephalosporins, dapsone, gentamycin, gold, lithium, NSAIDs, penicillins, phenolphthalein, phenytoin, sulphonamides
, tetracyclines, and thiazides.
have been reported to have some side effect, such as hypersensitivity and cytopenia (9, 10).
fortuitum Amikacin, cefoxitin, ciprofloxacin, moxifloxacin, clarithromycin, doxycycline, sulphonamides
, linezolid and imipenem M.