Sydney Brenner


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Brenner, Sydney,

1927–, British molecular biologist, Ph.D. Oxford, 1954. He was director of the MRC Laboratory of Molecular Biology in Cambridge, England (1979–86), and director of the MRC Molecular Genetics Unit (1986–91) before joining (1996–) the Salk Institute, La Jolla, Calif., where he is currently distinguished research professor. With H. Robert HorvitzHorvitz, H. Robert
(Howard Robert Horivtz), 1947–, American geneticist, b. Chicago, Ill., Ph.D. Harvard, 1974. Horvitz has been a professor at the Massachusetts Institute of Technology since 1978.
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 and John E. SulstonSulston, Sir John Edward,
1942–2018, British molecular biologist, Ph.D. Cambridge, 1966. He was staff scientist at the MRC Laboratory of Molecular Biology in Cambridge, England, from 1969 to 1992, when he became founding director (until 2000) of what is now the Wellcome
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, Brenner received the 2002 Nobel Prize in Medicine or Physiology for discoveries relating to the genetic regulation of organ development and programmed cell death. Brenner is credited with laying the foundation for the work by establishing the nematode Caenorhabditis elegans as a model organism for genetic studies. The .04-in.-long (1-mm) worm has a short life cycle, allowing researchers to learn substantial information about organ development and cell death in a relatively short period of time, and it is transparent, enabling cell division to be observed directly under a microscope. Brenner demonstrated that a chemical compound could induce gene mutations in the nematode and that different mutations could be tied to specific genes.
References in periodicals archive ?
elegans es un modelo experimental utilizado por numerosos investigadores, desde que a fines del siglo pasado el biologo molecular Sydney Brenner lo utilizo para sus investigaciones, lo cual le valio el Premio Nobel de Fisiologia o Medicina en 2002.
The 2016 SNAS Fellowships were presented by Dr Sydney Brenner, the 2002 Nobel Laureate for Physiology or Medicine and one of the worlds pioneers in genetics and molecular biology, at a ceremony held at the NUSS Kent Ridge Guild House today.
It was almost 50 years ago that the Cambridge-based geneticist Sydney Brenner pioneered the use of C.
Horvitz shared the 2002 Nobel Prize in Physiology or Medicine with Sydney Brenner and John Sulston.
Nobel Laureate Sydney Brenner who also suggested the formation of HUGO, delivered a keynote lecture on Reading the Human Genome.
of Texas Southwestern Medical Center at Dallas) presents this fascinating biography of Sydney Brenner, one of the heroes of molecular biology.
Sydney Brenner, Francois Jacob and Matthew Meselson show that messenger RNA (above) carries the information required to make proteins.
He graduated in 1950, always claiming this to have been the greatest Wits graduating class ever, with such notable names as Philip Tobias, Sydney Brenner and Priscilla Kincaid-Smith.
elegans, the famous worm subject of many studies on embryonic development and developmental genetic, even though Sydney Brenner, who pioneered using the worm as a model organism, is briefly mentioned.
Cuando la asamblea Nobel del Instituto Karolinska otorgo el Premio Nobel de Medicina a Sydney Brenner, H.
Nobel Prize winner Dr Sydney Brenner, who devised the method for obtaining sequence information from thousands of genomes simultaneously, said scientists did not need to know everything about every gene in order to combat disease.
He shares the Nobel Prize with ex-colleague Dr Sydney Brenner and American scientist Robert Horvitz.

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