The researchers observed that when calcium levels in the nerve cell increase, such as upon neuronal signalling, the alpha-synuclein binds to synaptic vesicles
at multiple points causing the vesicles to come together.
, presynaptic active zone, and PSDs can be recognized.
Given that spontaneous mEPSCs are believed to be the postsynaptic response to a single spontaneously released synaptic vesicle
(Wiegert et al.
Beta- amyloid causes depletion of synaptic vesicles
leading to neurotransmission failure.
Timothy Ryan, professor of biochemistry at Weill Cornell Medical College, demonstrates that individual neurons somehow control the speed by which they recycle synaptic vesicles
that store neurotransmitters before they are released.
When a pain signal is transmitted, the channel opens and the calcium concentration increases, triggering the release of neurotransmitters from synaptic vesicles
, thereby sending the pain signal to the brain where it is perceived as pain.
The gene involved with EIC is responsible for making new synaptic vesicles
and enabling nerve communication to continue.
Selective depletion of clear synaptic vesicles
and enhanced quantal transmitter release at frog motor nerve endings produced by trachynilysin, a protein toxin isolated from stonefish (Synanceia trachynis).
The proteins produced in the nucleus are transported via microtubules and neurofilaments to the synapses that contain mitochondria, which are responsible for energy production, and the synaptic vesicles
that store the different neurotransmitters (Figure 3).
It is worth noting that lipid-derived compounds do not have to be released from synaptic vesicles
The postsynaptic terminals were seen to contain subsynaptic cisterns formed by membranes of smooth endoplasmic reticulum beneath the postsynaptic density, whereas the presynaptic terminal showed numerous electron transparent synaptic vesicles
2+] dependent kinases, on releasing synaptic vesicles
from actin filaments, may accelerate vesicles to the presynaptic membrane.