Synergist


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synergist

[′sin·ər‚jist]
(anatomy)
A muscle that assists a prime mover muscle in performing a specific action.
(materials)
A material that enhances the effect of another material so that when they are combined the total effect is greater than the sum of their individual effects.

Synergist

 

(1) In anatomy and physiology, a muscle (or group of muscles) that acts jointly and functions homogeneously with another muscle (or group of muscles) in the same movement.

Examples of synergists in mammals (including humans) are the external intercostal and intercartilagtnous muscles and the muscles of the diaphragm, which, by contracting simultaneously, ensure the act of inhalation. Muscles that act together in performing a particular movement may be antagonists in the execution of other movements. The phenomenon of synergism is ensured by the regulatory activity of the central nervous system.

(2) In pharmacology, one of several medicinal agents used jointly whose combined effect on the body exceeds the effect exerted by each separately. Direct synergists act on the same reactive systems of the body, such as the simultaneous influence of two adrenomimetic substances. Indirect synergists exert the same end effect but differ in their mechanisms of action. For example, adrenaline and atropine act along different pathways to produce dilatation of the pupils; when taken together, the overall effect of these substances on the pupil exceeds the effect of each separately.

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Synergist efficacy of piperonyl butoxide with deltamethrin as pyrethroid insecticide on Culex tritaeniorhynchus (Diptera: Culicidae) and other mosquitoe species.
Were evaluated the following treatments: 1) empty trap (without attractants), 2) trap with pheromone without synergist, 3) trap with pheromone + 400 g of "maguey espadin criollo" (Agave angustifolia Haw.) tissue, 4) trap with pheromone + 400 g of "maguey espadin oaxaqueno" (Agave angustifolia Haw.) tissue, 5) trap with pheromone + 400 g of "maguey papalote" (Agave cupreata Trel.) tissue, 6) trap with pheromone + 400 g of ripped pineapple fruit (Ananas comosus L.), 7) trap with pheromone + 400 g of ripped banana (Musa paradisiaca L.) fruit, 8) trap with pheromone + 400 g of sugarcane (Saccharum officinarum L.) tissue, 9) trap with pheromone + 100 g of tuberose (Polianthes tuberosa L.) flower, and 10) trap with pheromone + 400 g ripped of guava (Psidium guajava L.) fruit.
It is well known that IOD is an efficient synergist for the sensitizer/co-initiator system.
The utility of camptothecin as a synergist of Bacillus thuringiensis var.
Test design of fixed dispersed oil suspension formulation mesotrione TC (15%), OF-3472 (3%) dispersant and emulsifier OF-3468 (20%): 6300 (3%) synergist and stabilizer MF-33 (2%), a thickening agent SK04 (Suzhou Hui material), PT-L88 (Hunan Peng Thai) quality the number of points were: 0.5%, 1%, 1.5%, with a solvent filled to 100% methyl oleate, the measurement of different types and amount of thickening agent on the dispersion effect of dumping and stability of the oil suspension agent, the results (Table 5) showed that the SK04 content is 1%, dispersed oil suspension dumping and stability the best.
Antidepressant polypharmacy is another type of multimodal treatment that needs to be compared to the use of a single antidepressant and a synergist; there may be situations in which two different antidepressants result in better outcomes than the use of a single antidepressant and a synergist.
The high prices of synthetic synergist compounds, some other compounds which are economically reasonable and low risk, are used for increasing the poisoning effect [5].
Animal Surgeries: Following genotypic determination, [FoxO1.sup.+/-] and WT mice were divided into two groups (n = 10-12 per group): (a) 14-day sham surgery (control); and (b) 14-day synergist ablation (overload).
The gram-negative cells have two membranes, with space in between that not only makes them more difficult to treat but also requires a remedy that will scavenge the endotoxins shed from the outer cell wall and a synergist that will act against the efflux pump in the cell.
Vitamin K is an excellent synergist fat-soluble vitamin which I often recommend along with vitamin D.
M2 EQUITYBITES-November 30, 2011-Albemarle Corporation partners with Louisiana State University to develop new techniques in flame retardant and synergist analysis(C)2011 M2 COMMUNICATIONS http://www.m2.com